131123-76-7
131123-76-7 structure
- Name: 5,7-Dichlorokynurenic acid
- Chemical Name: 5,7-dichlorokynurenic acid sodium salt
- CAS Number: 131123-76-7
- Molecular Formula: C10H5Cl2NO3
- Molecular Weight: 258.05800
- Catalog: Signaling Pathways Membrane Transporter/Ion Channel iGluR
- Create Date: 2018-06-11 17:43:37
- Modify Date: 2024-01-05 13:04:09
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5,7-Dichlorokynurenic acid (5,7-DCKA) is a selective and competitive antagonist of the glycine site on NMDA receptor with a KB of 65 nM. 5,7-Dichlorokynurenic acid, a derivative of kynurenic acid, reduced NMDA-induced neuron injury in rat cortical cell cultures[1].
| Name | 5,7-dichlorokynurenic acid sodium salt |
|---|---|
| Synonyms |
5,7-DICHLOROKYNURENIC ACID
5,7-Dichlorokynurenic acid sodium salt 5,7-Dichorokynurenic acid 5,7-dichloro-4-hydroxy-2-carboxyquinoline MFCD00674925 5,7-DCKA 5,7-DICHLORO-4-HYDROXYQUINOLINE-2-CARBOXYLIC ACID 5,7-Dichloro-4-hydroxy-2-quinolinecarboxylic acid 5,7-DICHLOROKYNURENIC ACID POTENT EXCITA TORY AMI 2-Quinolinecarboxylic acid,5,7-dichloro-4-hydroxy 5,7-dichlorokynurenic acid sodium 5,7-Dichloroquinurenic acid 5,7-Dichlor-4-hydroxy-chinolin-2-carbonsaeure |
| Description | 5,7-Dichlorokynurenic acid (5,7-DCKA) is a selective and competitive antagonist of the glycine site on NMDA receptor with a KB of 65 nM. 5,7-Dichlorokynurenic acid, a derivative of kynurenic acid, reduced NMDA-induced neuron injury in rat cortical cell cultures[1]. |
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| Related Catalog | |
| References |
| Molecular Formula | C10H5Cl2NO3 |
|---|---|
| Molecular Weight | 258.05800 |
| Exact Mass | 256.96500 |
| PSA | 70.42000 |
| LogP | 2.94540 |
| Appearance | solid | light yellow |
| Storage condition | Desiccate at RT |
| Water Solubility | 0.1 M NaOH: soluble |
| Hazard Codes | Xi |
|---|---|
| Risk Phrases | R36/37/38:Irritating to eyes, respiratory system and skin . |
| Safety Phrases | S26-S36 |
| WGK Germany | 3 |
| HS Code | 2933499090 |
| Precursor 2 | |
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| DownStream 3 | |
| HS Code | 2933499090 |
|---|---|
| Summary | 2933499090. other compounds containing in the structure a quinoline or isoquinoline ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |