64284-64-6

64284-64-6 structure
64284-64-6 structure
  • Name: FF-MAS
  • Chemical Name: 4,4-dimethyl-5α-cholesta-8,14,24-trien-3β-ol
  • CAS Number: 64284-64-6
  • Molecular Formula: C29H46O
  • Molecular Weight: 410.67500
  • Catalog: Research Areas Metabolic Disease
  • Create Date: 2017-12-31 20:47:24
  • Modify Date: 2024-01-14 21:40:21
  • FF-MAS is a potent meiotic maturation agonist. FF-MAS promotes meiotic maturation and preimplantation development of mouse oocytes maturing in vitro. FF-MAS promotes the completion of meiotic maturation to metaphase II (MII) and improves competence to complete the 2-cell stage to blastocyst transition[1][2].

Name 4,4-dimethyl-5α-cholesta-8,14,24-trien-3β-ol
Synonyms (3R,5S,10S,13S,17S)-4,4,10,13-tetramethyl-17-[(2R)-6-methylhept-5-en-2-yl]-1,2,3,5,6,7,11,12,16,17-decahydrocyclopenta[a]phenanthren-3-ol
(3β,5α)-4,4-Dimethylcholesta-8,14,24-trien-3-ol
4,4-dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol
Description FF-MAS is a potent meiotic maturation agonist. FF-MAS promotes meiotic maturation and preimplantation development of mouse oocytes maturing in vitro. FF-MAS promotes the completion of meiotic maturation to metaphase II (MII) and improves competence to complete the 2-cell stage to blastocyst transition[1][2].
Related Catalog
In Vitro FF-MAS (1 µM;16-17 小时) 促进减数分裂成熟的完成和卵母细胞完成从 2 细胞阶段到囊胚转变的能力[1]。
References

[1]. Marín Bivens CL, et al. A synthetic analogue of meiosis-activating sterol (FF-MAS) is a potent agonist promoting meiotic maturation and preimplantation development of mouse oocytes maturing in vitro. Hum Reprod. 2004 Oct;19(10):2340-4.  

[2]. Thorsten Blume, et al. Two Syntheses of FF-MAS. Org. Lett. 2003, 5, 11, 1837-1839.

Density 1g/cm3
Boiling Point 512.6ºC at 760 mmHg
Molecular Formula C29H46O
Molecular Weight 410.67500
Flash Point 221.9ºC
Exact Mass 410.35500
PSA 20.23000
LogP 8.00910
Index of Refraction 1.541
Precursor  3

DownStream  0