68617-64-1

68617-64-1 structure

Name: 3-(2-Pyridyldithio)propanoic Acid
Chemical Name: 3-(pyridin-2-yldisulfanyl)propanoic acid
CAS Number: 68617-64-1
Molecular Formula: C₈H₉NO₂S₂
Molecular Weight: 215.29300
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2018-12-05 16:22:31
Modify Date: 2024-01-08 18:47:42
3-(2-Pyridyldithio)propanoic Acid is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	3-(pyridin-2-yldisulfanyl)propanoic acid
Synonyms	2-carboxyethyl-pyridin-2-yldisulphide 3-(2-Pyridinyldithio)propanoic Acid 3-(2-Pyridyldithio)propanoic acid Propanoic acid,3-(2-pyridinyldithio) 2-Carboxyethyl 2-Pyridyl Disulfide 3-(PYRIDIN-2-YLDITHIO)PROPANOIC ACID 3-(2-pyridinyldisulfanyl)propanoic acid 3-(pyridin-2-yldithio)-propionic acid 3-(2-Pyridyldithio)propionic acid 3-(pyridin-2-yldisulfanyl)propionic acid

Description	3-(2-Pyridyldithio)propanoic Acid is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	Alkyl-Chain
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562