2127-03-9
2127-03-9 structure
- Name: 2,2′-Dipyridyl disulfide
- Chemical Name: 2-(pyridin-2-yldisulfanyl)pyridine
- CAS Number: 2127-03-9
- Molecular Formula: C10H8N2S2
- Molecular Weight: 220.31
- Catalog: Pharmaceutical intermediate Heterocyclic compound Pyridine compound Pyridine derivative
- Create Date: 2018-04-10 08:00:00
- Modify Date: 2026-07-09 11:55:13
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2,2′-Dipyridyl disulfide is a useful reagent for the determination of sulfhydryl groups. 2,2′-Dipyridyl disulfide is a common reagent in peptide chemistry, often used in oxidation–reduction condensations to form peptide bonds or in coupling reactions to form disulfide-linked heterodimers[1].
| Name | 2-(pyridin-2-yldisulfanyl)pyridine |
|---|---|
| Synonyms |
1,2-Di(pyridin-2-yl)disulfide
di(2-pyridyl) disulfide ALDRITHIOL(TM)-2 2,2'-Disulphanediyldipyridine, 2,2'-Dithiodipyridine Bis(2-pyridinyl) disulfide Pyridine, 2,2-dithiobis 2,2'-Dipyridyl disulfide Dipyridyldisulfide 2,2'-DIHYDROXYDIPHENYLMETHANE 2,2'-Dithiobispyridine ALDRITHIOL-2 2-PDS MFCD00006287 Dithiodipyridine 2,2'-Dipyridyl Disulfide [for Ptide Synthesis] 2,2‘-Dithiodipyridine 2,2′-dipyridyldisulfide Bis(pyridin-2-yl) disulfide 2,2'-Dithiodipyridine, >= Aldrithiol-2 Nsc 2,2'- Dipyridil disulfide 2,2'-Dithiodipyridine ISO 9001：2015 REACH Pyridine, 2,2'-dithiodi Bis(2-pyridyl) disulfide 2,2'-Bipyridyldisulfide 2,2''-Dithiodipyridine Di(pyridin-2-yl) disulphide 2-Aldrithiol 2,2'-Dipyridinyl disulfide Aldrithiol™-2 2,2'-Dithiodipyridin 2,2'-DipyridylDisulfide[forPtideSynthesis]> 2,2'-Dithiodipyridine 4,4′-dipyridyldisulfide 9-[(3aS,6-6-(hydroxymethyl)-2,2-dimethyl-3a,4,6,6a-tetrahydrofuro[3,4-d][1,3]dioxol-4-yl]-3H-purin-6-one Bis(pyridin-2-yl) disulphide 2,2'-Dipyridyl disuldide pyridyl disulfide 2-Pyridinyl disulfide 1,2-Bis(2-pyridinyl) Disulfide 1,2-Di(pyridin-2-yl)disulfane 2-Pyridin-2-yldisulfanylpyridine EINECS 218-343-1 2-Dipyridyl disulfide Aldrithiol 2 Aldritiol Di(pyridin-2-yl) disulfide 2,2'-Dithiopyridine bis-pyridin-2-yl-disulfide 2,2'-DIPYRIDYL DISULPHIDE 2,2''-DIPYRIDYL DISULFIDE pyridyldisulfide 2,2μ-Dipyridyl disulfide, 2,2μ-Dithiodipyridine 2,2'-Disulfanediyldipyridine Aldrithiol 1,2-Di(pyridin-2-yl 2-(2-Pyridyldisulfanyl)pyridine Di(2-pyridyl) persulfide 2-(PYRIDIN-2-YLDITHIO)PYRIDINE 2,2′-dipyridyl disulfide 2-(2-Pyridinyldisulfanyl)pyridine Di-2-Pyridyl disulfide 2,2'-Dipyridyl disulfide|||OPSS|||Aldrithiol 2|||Orthopyridyl disulfide 2,2'-Dithiobis(pyridine) 2PDS Aldrithol-2 2-PYRIDINYL DISULFIDE 2-Pyridyl disulfide 2,2'-dipyridinyl disulfide |
| Description | 2,2′-Dipyridyl disulfide is a useful reagent for the determination of sulfhydryl groups. 2,2′-Dipyridyl disulfide is a common reagent in peptide chemistry, often used in oxidation–reduction condensations to form peptide bonds or in coupling reactions to form disulfide-linked heterodimers[1]. |
|---|---|
| Related Catalog | |
| In Vitro | Formation of intramolecular S–S bonds can be dramatically accelerated by addition of a 2,2′-Dipyridyl disulfide (2-PDS) solution to an air-oxidized mixture of cysteine-containing peptides[1]. |
| References |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 356.1±17.0 °C at 760 mmHg |
| Melting Point | 56-58 °C(lit.) |
| Molecular Formula | C10H8N2S2 |
| Molecular Weight | 220.31 |
| Flash Point | 169.2±20.9 °C |
| Exact Mass | 220.012894 |
| PSA | 76.38000 |
| LogP | 2.53 |
| Vapour Pressure | 0.0±0.8 mmHg at 25°C |
| Index of Refraction | 1.694 |
| Storage condition | 2-8°C |
| Water Solubility | 5 g/L (20 ºC) |
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H315-H319-H335 |
| Precautionary Statements | P261-P305 + P351 + P338 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xn:Harmful; |
| Risk Phrases | R20/22;R37 |
| Safety Phrases | S36/37/39-S37/39-S25-S22 |
| RIDADR | UN3335 9 |
| WGK Germany | 3 |
| Precursor 8 | |
|---|---|
| DownStream 10 | |
