386704-15-0
386704-15-0 structure
- Name: methyl 3-oxo-3-(6-(trifluoromethyl)pyridin-3-yl)propanoate
- Chemical Name: methyl 3-oxo-3-[6-(trifluoromethyl)pyridin-3-yl]propanoate
- CAS Number: 386704-15-0
- Molecular Formula: C10H8F3NO3
- Molecular Weight: 247.17100
- Catalog: Research Areas Metabolic Disease
- Create Date: 2018-04-25 08:00:00
- Modify Date: 2024-01-16 14:14:48
-
11β-HSD1-IN-8 (compound c6a) is a 11β‑HSD1 inhibitor with an IC50 value of 2.3 μM for human 11β‑HSD1. 11β-HSD1-IN-8 can be used for the research of diabetes and cognitive decline[1].
| Name | methyl 3-oxo-3-[6-(trifluoromethyl)pyridin-3-yl]propanoate |
|---|---|
| Synonyms | MFCD01862654 |
| Description | 11β-HSD1-IN-8 (compound c6a) is a 11β‑HSD1 inhibitor with an IC50 value of 2.3 μM for human 11β‑HSD1. 11β-HSD1-IN-8 can be used for the research of diabetes and cognitive decline[1]. |
|---|---|
| Related Catalog | |
| Target |
IC50: 2.3 μM (human 11β‑HSD)[1] |
| In Vitro | 11β-HSD1-IN-8 (0-50 μM) inhibits human and rat 11β‑HSD1 with IC50 values of 2.3 μM and ＞50 μM, respectively[1]. |
| Density | 1.341g/cm3 |
|---|---|
| Boiling Point | 295.5ºC at 760 mmHg |
| Melting Point | 60-62ºC |
| Molecular Formula | C10H8F3NO3 |
| Molecular Weight | 247.17100 |
| Flash Point | 132.5ºC |
| Exact Mass | 247.04600 |
| PSA | 56.26000 |
| LogP | 1.84620 |
| Index of Refraction | 1.459 |
| Hazard Codes | Xi |
|---|---|
| HS Code | 2933399090 |
| HS Code | 2933399090 |
|---|---|
| Summary | 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |