38451-63-7

38451-63-7 structure

Name: Asatone
Chemical Name: asatone
CAS Number: 38451-63-7
Molecular Formula: C₂₄H₃₂O₈
Molecular Weight: 448.50600
Catalog: Research Areas Inflammation/Immunology
Create Date: 2018-02-14 08:00:00
Modify Date: 2024-01-05 23:47:54
Asatone is an active component isolated from Radix et Rhizoma Asari, with anti-inflammatory effect via activation of NF-κB and donwn regulation of p-MAPK (ERK, JNK and p38) pathways[1].

Name	asatone

Description	Asatone is an active component isolated from Radix et Rhizoma Asari, with anti-inflammatory effect via activation of NF-κB and donwn regulation of p-MAPK (ERK, JNK and p38) pathways[1].
Related Catalog	Research Areas >> Inflammation/Immunology
Target	NF-κB[1]
References	[1]. Chang HY, et al. Asatone Prevents Acute Lung Injury by Reducing Expressions of NF-[Formula: see text]B, MAPK and Inflammatory Cytokines. Am J Chin Med. 2018;46(3):651-671.

Density	1.19g/cm3
Boiling Point	536.1ºC at 760 mmHg
Molecular Formula	C₂₄H₃₂O₈
Molecular Weight	448.50600
Flash Point	228.9ºC
Exact Mass	448.21000
PSA	89.52000
LogP	2.35650
Index of Refraction	1.533

67-56-1

6627-88-9

~21%

38451-63-7

Literature: Kuerti, Laszlo; Szilagyi, Laszlo; Antus, Sandor; Nogradi, Mihaly European Journal of Organic Chemistry, 1999 , # 10 p. 2579 - 2582

67-56-1

6627-88-9

66463-79-4

66463-76-1

Detail

Literature: Nishiyama, Atsuko; Eto, Hideo; Terada, Yukimasa; Iguchi, Masanobu; Yamamura, Shosuke Chemical and Pharmaceutical Bulletin, 1983 , vol. 31, # 8 p. 2820 - 2833

67-56-1

6627-88-9

66463-74-9

66463-79-4

Detail

Literature: Nishiyama, Atsuko; Eto, Hideo; Terada, Yukimasa; Iguchi, Masanobu; Yamamura, Shosuke Chemical and Pharmaceutical Bulletin, 1983 , vol. 31, # 8 p. 2820 - 2833

Precursor 2
67-56-1 6627-88-9
DownStream 4
6627-88-9 78660-19-2 70280-34-1 51895-33-1

56-41-7	108-65-6
56-35-9	64-17-5
67-56-1	108-88-3
141-78-6	1310-73-2
13463-67-7	1333-86-4