Asatone

Modify Date: 2024-01-05 23:47:54

Asatone Structure
Asatone structure
Common Name Asatone
CAS Number 38451-63-7 Molecular Weight 448.50600
Density 1.19g/cm3 Boiling Point 536.1ºC at 760 mmHg
Molecular Formula C24H32O8 Melting Point N/A
MSDS N/A Flash Point 228.9ºC

 Use of Asatone


Asatone is an active component isolated from Radix et Rhizoma Asari, with anti-inflammatory effect via activation of NF-κB and donwn regulation of p-MAPK (ERK, JNK and p38) pathways[1].

 Names

Name asatone

 Asatone Biological Activity

Description Asatone is an active component isolated from Radix et Rhizoma Asari, with anti-inflammatory effect via activation of NF-κB and donwn regulation of p-MAPK (ERK, JNK and p38) pathways[1].
Related Catalog
Target

NF-κB[1]

References

[1]. Chang HY, et al. Asatone Prevents Acute Lung Injury by Reducing Expressions of NF-[Formula: see text]B, MAPK and Inflammatory Cytokines. Am J Chin Med. 2018;46(3):651-671.

 Chemical & Physical Properties

Density 1.19g/cm3
Boiling Point 536.1ºC at 760 mmHg
Molecular Formula C24H32O8
Molecular Weight 448.50600
Flash Point 228.9ºC
Exact Mass 448.21000
PSA 89.52000
LogP 2.35650
Index of Refraction 1.533

 Synthetic Route

~21%

Asatone Structure

Asatone

CAS#:38451-63-7

Literature: Kuerti, Laszlo; Szilagyi, Laszlo; Antus, Sandor; Nogradi, Mihaly European Journal of Organic Chemistry, 1999 , # 10 p. 2579 - 2582

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Detail
Literature: Nishiyama, Atsuko; Eto, Hideo; Terada, Yukimasa; Iguchi, Masanobu; Yamamura, Shosuke Chemical and Pharmaceutical Bulletin, 1983 , vol. 31, # 8 p. 2820 - 2833

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Detail
Literature: Nishiyama, Atsuko; Eto, Hideo; Terada, Yukimasa; Iguchi, Masanobu; Yamamura, Shosuke Chemical and Pharmaceutical Bulletin, 1983 , vol. 31, # 8 p. 2820 - 2833
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