CHEMICAL IDENTIFICATION
 - 
  RTECS NUMBER :
 
 
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  GL7375000
 
 
 
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  CHEMICAL NAME :
 
 
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  Copper, (5-((4'-((2,5-dihydroxy-4-((2-hydroxy-5-sulfophenyl)a zo)phenyl)azo)(1,1'-b iphenyl)- 4-yl)azo)-2-hydroxybenzoato(2-))-, disodium salt
 
 
 
 - 
  CAS REGISTRY NUMBER :
 
 
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  16071-86-6
 
 
 
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  LAST UPDATED :
 
 
 - 
  199712
 
 
 
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  DATA ITEMS CITED :
 
 
 - 
  23
 
 
 
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  MOLECULAR FORMULA :
 
 
 - 
  C31-H18-Cu-N6-O9-S.2Na
 
 
 
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  MOLECULAR WEIGHT :
 
 
 - 
  760.13
 
 
 
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
 - 
  TYPE OF TEST :
 
 
 - 
  LD50 - Lethal dose, 50 percent kill
 
 
 
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  ROUTE OF EXPOSURE :
 
 
 - 
  Oral
 
 
 
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  SPECIES OBSERVED :
 
 
 - 
  Rodent - rat
 
 
 
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  DOSE/DURATION :
 
 
 - 
  12060 mg/kg
 
 
 
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  TOXIC EFFECTS :
 
 
 - 
  Details of toxic effects not reported other than lethal dose value
 
 
 
 - 
  TYPE OF TEST :
 
 
 - 
  LDLo - Lowest published lethal dose
 
 
 
 - 
  ROUTE OF EXPOSURE :
 
 
 - 
  Oral
 
 
 
 - 
  SPECIES OBSERVED :
 
 
 - 
  Rodent - rabbit
 
 
 
 - 
  DOSE/DURATION :
 
 
 - 
  2 gm/kg
 
 
 
 - 
  TOXIC EFFECTS :
 
 
 - 
  Details of toxic effects not reported other than lethal dose value
 
 
 
 - 
  TYPE OF TEST :
 
 
 - 
  TDLo - Lowest published toxic dose
 
 
 
 - 
  ROUTE OF EXPOSURE :
 
 
 - 
  Oral
 
 
 
 - 
  SPECIES OBSERVED :
 
 
 - 
  Rodent - rat
 
 
 
 - 
  DOSE/DURATION :
 
 
 - 
  2625 mg/kg/5W-C
 
 
 
 - 
  TOXIC EFFECTS :
 
 
 - 
  Tumorigenic - neoplastic by RTECS criteria Liver - tumors
 
 
 
 - 
  TYPE OF TEST :
 
 
 - 
  TD - Toxic dose (other than lowest)
 
 
 
 - 
  ROUTE OF EXPOSURE :
 
 
 - 
  Oral
 
 
 
 - 
  SPECIES OBSERVED :
 
 
 - 
  Rodent - rat
 
 
 
 - 
  DOSE/DURATION :
 
 
 - 
  6825 mg/kg/13W-C
 
 
 
 - 
  TOXIC EFFECTS :
 
 
 - 
  Tumorigenic - equivocal tumorigenic agent by RTECS criteria Liver - tumors
 
 
 
 - 
  TYPE OF TEST :
 
 
 - 
  Unscheduled DNA synthesis
 
 
 
MUTATION DATA
 - 
  TYPE OF TEST :
 
 
 - 
  Body fluid assay
 
 
 
 - 
  TEST SYSTEM :
 
 
 - 
  Rodent - rat Bacteria - Salmonella typhimurium
 
 
 
 - 
  DOSE/DURATION :
 
 
 - 
  250 umol/kg
 
 
 
 - 
  REFERENCE :
 
 
 - 
  TXCYAC Toxicology. (Elsevier Scientific Pub. Ireland, Ltd., POB 85, Limerick, Ireland) V.1- 1973- Volume(issue)/page/year: 31,271,1984 *** REVIEWS *** IARC Cancer Review:Animal Limited Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 29,321,1982 IARC Cancer Review:Animal Sufficient Evidence IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,125,1987 IARC Cancer Review:Human Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 29,321,1982 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-FINLAND;Carcinogen JAN 1993 OEL-FRANCE;Carcinogen JAN 1993 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - M1412 No. of Facilities: 37 (estimated) No. of Industries: 3 No. of Occupations: 11 No. of Employees: 1112 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - M1412 No. of Facilities: 119 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 830 (estimated)
 
 
  
                                    
                                 
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