35692-88-7

35692-88-7 structure
35692-88-7 structure
  • Name: (2H)Formamide
  • Chemical Name: deuterioformamide
  • CAS Number: 35692-88-7
  • Molecular Formula: CH2DNO
  • Molecular Weight: 46.047
  • Catalog: Research Areas Others
  • Create Date: 2018-05-08 08:00:00
  • Modify Date: 2024-01-04 09:15:55
  • Formamide-d1 is the deuterium labeled Formamide[1]. Formamide is an amide derived from formic acid and has been used as solvent for many ionic compounds.

Name deuterioformamide
Synonyms (H)Formamide
C-Deuterio-formamid
d1-N,N-formamide
Formamide-1-d
Formamide-d
formamide-d1
MFCD01074135
C-deuterio-formamide
Description Formamide-d1 is the deuterium labeled Formamide[1]. Formamide is an amide derived from formic acid and has been used as solvent for many ionic compounds.
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

Density 1.0±0.1 g/cm3
Boiling Point 210.5±9.0 °C at 760 mmHg
Melting Point 2-3ºC(lit.)
Molecular Formula CH2DNO
Molecular Weight 46.047
Flash Point 81.1±18.7 °C
Exact Mass 46.027740
PSA 43.09000
LogP -1.51
Vapour Pressure 0.2±0.4 mmHg at 25°C
Index of Refraction 1.370
Symbol GHS08
GHS08
Signal Word Danger
Hazard Statements H351-H360D-H373
Precautionary Statements P201-P260-P280-P308 + P313
Target Organs Blood
Hazard Codes T: Toxic;
Risk Phrases 61-37/38-41
Safety Phrases 53-23-26-36/37/39-45
RIDADR NONH for all modes of transport

~97%

35692-88-7 structure

35692-88-7

Literature: Threadgill, Michael D.; Gledhill, Adrian P. Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1986 , p. 873 - 876

~%

35692-88-7 structure

35692-88-7

Literature: Ha, Jeong-Hyon; Kim, Yung Sam; Hochstrasser, Robin M. Journal of Chemical Physics, 2006 , vol. 124, # 6 art. no. 064508
Precursor  2

DownStream  1