4548-34-9

4548-34-9 structure

Name: Tranylcypromine (2-PCPA) HCl
Chemical Name: tranylcypromine hydrochloride
CAS Number: 4548-34-9
Molecular Formula: C₉H₁₂ClN
Molecular Weight: 169.65100
Catalog: Signaling Pathways Epigenetics Histone Demethylase
Create Date: 2018-08-24 16:55:47
Modify Date: 2024-01-13 15:10:48
(1S,2R)-Tranylcypromine hydrochloride is a potent antidepressant agent. (1S,2R)-Tranylcypromine hydrochloride can inhibits MAO and LSD1[1][2].

Name	tranylcypromine hydrochloride
Synonyms	Tranylcypromine (2-PCPA) HCl (1S,2R)-2-Phenylcyclopropan-1-amine hydrochloride Tranylcypromine (+)-TRANYLCYPROMINE HYDROCHLORIDE

Description	(1S,2R)-Tranylcypromine hydrochloride is a potent antidepressant agent. (1S,2R)-Tranylcypromine hydrochloride can inhibits MAO and LSD1[1][2].
Related Catalog	Signaling Pathways >> Epigenetics >> Histone Demethylase Signaling Pathways >> Neuronal Signaling >> Monoamine Oxidase Research Areas >> Neurological Disease
References	[1]. TetsuyaEzawa, et al. Amidation of carboxylic acids via the mixed carbonic carboxylic anhydrides and its application to synthesis of antidepressant (1S,2R)-tranylcypromine. Tetrahedron: Asymmetry. 15 December 2017;28(12):1690-1699. [2]. Valente S, et al. Pure Diastereomers of a Tranylcypromine-Based LSD1 Inhibitor: Enzyme Selectivity and In-Cell Studies. ACS Med Chem Lett. 2014 Dec 8;6(2):173-7.