114906-74-0
114906-74-0 structure
- Name: Ciwujianoside C3
- Chemical Name: ciwujianoside C3
- CAS Number: 114906-74-0
- Molecular Formula: C53H86O21
- Molecular Weight: 1059.24000
- Catalog: Signaling Pathways Immunology/Inflammation NO Synthase
- Create Date: 2017-09-17 19:33:10
- Modify Date: 2024-01-10 07:44:43
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Ciwujianoside C3, an orally active and brain penetrated compound, is isolated the leaves of Acanthopanax henryi Harms. Ciwujianoside C3 has anti-inflammatory effect and can reinforces object recognition memory[1][2].
| Name | ciwujianoside C3 |
|---|---|
| Synonyms |
.oleanolic acid α-L-arabinopyranosyl-28-O-α-L-rhamnopyranosyl-(1->4)-O-β-gentiobiosyl ester
3-O-α-L-arabinopyranosyl-28-O-α-L-rhamnopyranosyl-(1-4)-O-β-D-glucopyranosyl-(1-6)-O-β-D-glucopyranosyl ester of oleanolic acid .3-O-α-L-arabinopyranosyl-oleanolic acid 28-O-α-L-rhamnopyranosyl-(1->4)-β-D-gentiobiosyl ester .3β-O-α-L-arabinopyranosylolean-12-en-28-O-α-L-rhamnopyranosyl-(1->4)-β-D-glucopyranosyl-(1->6)-β-D-glucopyranoside .oleanolic acid-3-O-α-L-arabinopyranosyl-28-O-α-L-rhamnopyranosyl-(1->4)-O-β-D-glucopyranosyl-(1-6)-O-β-D-glucopyranoside |
| Description | Ciwujianoside C3, an orally active and brain penetrated compound, is isolated the leaves of Acanthopanax henryi Harms. Ciwujianoside C3 has anti-inflammatory effect and can reinforces object recognition memory[1][2]. |
|---|---|
| Related Catalog | |
| In Vitro | Cell Viability Assay[1] Cell Line: RAW 264.7 cells Concentration: 10 µM, 20 µM and 40 µM Incubation Time: 24 hours Result: Has no effect on cell cytotoxicity and inhibits NO production Western Blot Analysis[1] Cell Line: RAW 264.7 cells Concentration: 10 µM, 20 µM and 40 µM Incubation Time: 24 hours Result: Decreases p-ERK and p-JNK expression. RT-PCR[1] Cell Line: RAW 264.7 cells Concentration: 10 µM, 20 µM and 40 µM Incubation Time: 24 hours Result: Decreased COX-2 and iNOS mRNA expression in a dose-dependent manner. |
| In Vivo | Animal Model: Mice[1] Dosage: 0.5 mg/kg Administration: Oral administration; 0.5 mg/kg/day; 17 days Result: Reinforced object recognition memory. |
| References |
| Density | 1.43±0.1 g/cm3(Predicted) |
|---|---|
| Molecular Formula | C53H86O21 |
| Molecular Weight | 1059.24000 |
| Exact Mass | 1058.57000 |
| PSA | 333.67000 |
| Storage condition | 2-8°C |
