Ciwujianoside C3

Modify Date: 2024-01-10 07:44:43

Ciwujianoside C3 Structure
Ciwujianoside C3 structure
Common Name Ciwujianoside C3
CAS Number 114906-74-0 Molecular Weight 1059.24000
Density 1.43±0.1 g/cm3(Predicted) Boiling Point N/A
Molecular Formula C53H86O21 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Ciwujianoside C3


Ciwujianoside C3, an orally active and brain penetrated compound, is isolated the leaves of Acanthopanax henryi Harms. Ciwujianoside C3 has anti-inflammatory effect and can reinforces object recognition memory[1][2].

 Names

Name ciwujianoside C3
Synonym More Synonyms

 Ciwujianoside C3 Biological Activity

Description Ciwujianoside C3, an orally active and brain penetrated compound, is isolated the leaves of Acanthopanax henryi Harms. Ciwujianoside C3 has anti-inflammatory effect and can reinforces object recognition memory[1][2].
Related Catalog
In Vitro Cell Viability Assay[1] Cell Line: RAW 264.7 cells Concentration: 10 µM, 20 µM and 40 µM Incubation Time: 24 hours Result: Has no effect on cell cytotoxicity and inhibits NO production Western Blot Analysis[1] Cell Line: RAW 264.7 cells Concentration: 10 µM, 20 µM and 40 µM Incubation Time: 24 hours Result: Decreases p-ERK and p-JNK expression. RT-PCR[1] Cell Line: RAW 264.7 cells Concentration: 10 µM, 20 µM and 40 µM Incubation Time: 24 hours Result: Decreased COX-2 and iNOS mRNA expression in a dose-dependent manner.
In Vivo Animal Model: Mice[1] Dosage: 0.5 mg/kg Administration: Oral administration; 0.5 mg/kg/day; 17 days Result: Reinforced object recognition memory.
References

[1]. Kang DH, et al. Anti‑inflammatory effects of Ciwujianoside C3, extracted from the leaves of Acanthopanax henryi (Oliv.) Harms, on LPS‑stimulated RAW 264.7 cells.Mol Med Rep. 2016 Oct;14(4):3749-58.

[2]. https://www.ncbi.nlm.nih.gov/pubmed/31121888

 Chemical & Physical Properties

Density 1.43±0.1 g/cm3(Predicted)
Molecular Formula C53H86O21
Molecular Weight 1059.24000
Exact Mass 1058.57000
PSA 333.67000
Storage condition 2-8°C

 Synonyms

.oleanolic acid α-L-arabinopyranosyl-28-O-α-L-rhamnopyranosyl-(1->4)-O-β-gentiobiosyl ester
3-O-α-L-arabinopyranosyl-28-O-α-L-rhamnopyranosyl-(1-4)-O-β-D-glucopyranosyl-(1-6)-O-β-D-glucopyranosyl ester of oleanolic acid
.3-O-α-L-arabinopyranosyl-oleanolic acid 28-O-α-L-rhamnopyranosyl-(1->4)-β-D-gentiobiosyl ester
.3β-O-α-L-arabinopyranosylolean-12-en-28-O-α-L-rhamnopyranosyl-(1->4)-β-D-glucopyranosyl-(1->6)-β-D-glucopyranoside
.oleanolic acid-3-O-α-L-arabinopyranosyl-28-O-α-L-rhamnopyranosyl-(1->4)-O-β-D-glucopyranosyl-(1-6)-O-β-D-glucopyranoside
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