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88-10-8

88-10-8 structure
88-10-8 structure
Name Diethylcarbamyl chloride
Synonyms Carbamicchloride,diethyl
EINECS 201-798-5
MFCD00000636
diethylchloroformamide
N,N-diethylcarbamyl chloride
N,N-Diethylchloroformamide
Diethylcarbamyl chlo
diethylaminocarbonyl chloride
diethyl-carbamoylchlorid
N,N-diethylcarbamic acid chloride
diethyl-carbamicchlorid
Diethylaminoformyl chloride(D.E.C.C)
Diethylcarbamic chloride
diethylcarbamic acid chloride
Carbamic chloride, diethyl-
N,N-diethyl carbamoyl chloride
DECC
N,N-diethylaminocarbonyl chloride
Density 1.1±0.1 g/cm3
Boiling Point 186.0±9.0 °C at 760 mmHg
Melting Point −32 °C(lit.)
Molecular Formula C5H10ClNO
Molecular Weight 135.592
Flash Point 75.0±0.0 °C
Exact Mass 135.045090
PSA 20.31000
LogP 1.30
Vapour Pressure 0.7±0.4 mmHg at 25°C
Index of Refraction 1.446
Water Solubility HYDROLYSIS

CHEMICAL IDENTIFICATION

RTECS NUMBER :
FD4025000
CHEMICAL NAME :
Carbamoyl chloride, diethyl-
CAS REGISTRY NUMBER :
88-10-8
BEILSTEIN REFERENCE NO. :
0506687
LAST UPDATED :
199710
DATA ITEMS CITED :
11
MOLECULAR FORMULA :
C5-H10-Cl-N-O
MOLECULAR WEIGHT :
135.61
WISWESSER LINE NOTATION :
GVN2&2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration into the eye
SPECIES OBSERVED :
Rodent - rabbit
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0571246 ** ACUTE TOXICITY DATA **
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
2700 mg/kg
TOXIC EFFECTS :
Behavioral - coma Gastrointestinal - alteration in gastric secretion Blood - changes in spleen
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0571246
TYPE OF TEST :
LCLo - Lowest published lethal concentration
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
159 ppm/7H
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0571246
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
750 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: AD691-490
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
12840 mg/kg
TOXIC EFFECTS :
Skin and Appendages - dermatitis, other (after systemic exposure)
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0571246 ** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
5400 mg/kg/10D-I
TOXIC EFFECTS :
Gastrointestinal - hypermotility, diarrhea Related to Chronic Data - death
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0571246 ** TUMORIGENIC DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
43200 mg/kg/72W-I
TOXIC EFFECTS :
Tumorigenic - Carcinogenic by RTECS criteria Skin and Appendages - tumors Tumorigenic - tumors at site of application
REFERENCE :
JACTDZ Journal of the American College of Toxicology. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1-12, 1982-1993. Discontinued. Volume(issue)/page/year: 6(4),479,1987 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-GERMANY;Carcinogen JAN 1993
Symbol GHS07 GHS08
GHS07, GHS08
Signal Word Warning
Hazard Statements H302-H315-H319-H332-H335-H351
Precautionary Statements P261-P281-P305 + P351 + P338
Personal Protective Equipment Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes Xn:Harmful;
Risk Phrases R20/22;R36/37/38;R40
Safety Phrases S26-S36/37
RIDADR UN 3265 8/PG 3
WGK Germany 1
RTECS FD4025000
Packaging Group II
Hazard Class 8
HS Code 2903199000
HS Code 2903199000
Summary 2903199000 other saturated chlorinated derivatives of acyclic hydrocarbons。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%
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