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90-89-1

90-89-1 structure
90-89-1 structure

Name n,n-diethyl-4-methyl-1-piperazinecarboxamide
Synonyms Cbilazine
TIMTEC-BB SBB008185
N,N-diethyl-4-methyl-1-piperazin-4-iumcboxamide
1-Diethylcbamyl-4-methylpiperzine
diethycarbamazine
4-Methyl-piperazin-1-carbonsaeure-diaethylamid
rp3799
Aids-007958
ditrazinebase
1-Diethylcbamoyl-4-Methylpiperazine
Banocide
84L
Notezine
1-Methyl-4-diethylcbamoylpiperazine
n,n-diethyl-4-methyl-1-piperazinecboxamid
Cbamazine
N,N-diethyl-4-methylpiperazine-1-cboxamide
DIETHYL CBAMAZINE
Aids007958
diethlcbamazine
Diaethylcbamazinum
1-DIETHYLCBANOYL-4-METHYLPIPERAZINE
1-piperazinecboxamide,N,N-diethyl-4-methyl
5-0 (Hcl)
1-2 (Citrate)
Cbam palatabs
AI3-19612
Cicide
N,N-Diethylcbamazine
Cypip
DIETHYLCBAMAZINE //BP
Ditrazine base
Spatonin
Caracide
N,N-DIETHYL-4-METHYL-1-PIPERAZINECBOXAMIDE
Ethodryl
patonin
1-Diethylcbamyl-4-methylpiperazine
R.P
Caricide
1-(N,N-diethylcbamoyl)-4-methylpiperazine
N,N-Diethylcbamazine in methanol
1-Methyl-4-diethylcbamylpiperazine
1-(N,N-Diethylcbamyl)-4-methylpiperazine
Bitirazine
Cacide
4-methyl-piperazine-1-carboxylic acid diethylamide
Description Diethylcarbamazine is a microfilaricidal drug used originally in onchocerciasis and lymphatic filiariasis study[1].
Related Catalog
References

[1]. M García-Hernández, et al. Immunomodulatory effect of diethylcarbamazine in mice infected with Nocardia brasiliensis. Int Immunopharmacol. 2014 Nov;23(1):113-20.

Density 1.013g/cm3
Boiling Point 139ºC
Melting Point 137 - 140ºC
Molecular Formula C10H21N3O
Molecular Weight 199.29300
Flash Point 98ºC
Exact Mass 199.16800
PSA 26.79000
LogP 0.57140
Index of Refraction 1.492

CHEMICAL IDENTIFICATION

RTECS NUMBER :
TL1200000
CHEMICAL NAME :
1-Piperazinecarboxamide, N,N-diethyl-4-methyl-
CAS REGISTRY NUMBER :
90-89-1
BEILSTEIN REFERENCE NO. :
0143029
LAST UPDATED :
199701
DATA ITEMS CITED :
8
MOLECULAR FORMULA :
C10-H21-N3-O
MOLECULAR WEIGHT :
199.34

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Human - woman
DOSE/DURATION :
7300 mg/kg/1Y-I
TOXIC EFFECTS :
Skin and Appendages - dermatitis, allergic (after systemic exposure)
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
240 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
630 mg/kg
SEX/DURATION :
female 7-11 day(s) after conception
TOXIC EFFECTS :
Reproductive - Effects on Embryo or Fetus - fetal death
TYPE OF TEST :
Micronucleus test

MUTATION DATA

TEST SYSTEM :
Rodent - mouse
DOSE/DURATION :
40 mg/kg
REFERENCE :
TOLED5 Toxicology Letters. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1977- Volume(issue)/page/year: 44,7,1988 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X2728 No. of Facilities: 316 (estimated) No. of Industries: 1 No. of Occupations: 3 No. of Employees: 3161 (estimated) No. of Female Employees: 1581 (estimated)

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Literature: Journal of Organic Chemistry, , vol. 13, p. 144,149

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90-89-1

Literature: Journal of Organic Chemistry, , vol. 13, p. 144,149

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90-89-1

Literature: Journal of Organic Chemistry, , vol. 13, p. 144,149

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90-89-1

Literature: Bulletin des Societes Chimiques Belges, , vol. 58, p. 103,104

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Literature: Bulletin des Societes Chimiques Belges, , vol. 58, p. 103,104 Yakugaku Zasshi, , vol. 76, p. 605 Chem.Abstr., , p. 434

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Literature: Chemicke Zvesti, , vol. 6, p. 353

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90-89-1

Literature: DE923967 , ;
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