DC Chemicals Limited
China
Product Name: GS-2989
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Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 2-Naphthacenecarboxamide,7-chloro-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methylene-1,11-dioxo-,(4S,4aR,5S,5aR,12aS)-
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

2013-58-3

2013-58-3 structure

2013-58-3 structure

Name: GS-2989
Chemical Name: meclocycline
CAS Number: 2013-58-3
Molecular Formula: C₂₂H₂₁ClN₂O₈
Molecular Weight: 476.86
Catalog: API Antibiotics Tetracycline
Create Date: 2018-07-11 15:04:38
Modify Date: 2024-01-14 15:16:44
Meclocycline is a tetracycline derivative. The main target of tetracyclines is the bacterial ribosome[1].

Name	meclocycline
Synonyms	meclocyline Meclocycline(usan) GS-2989 Meclocycline base Chlormethylenecycline

Description	Meclocycline is a tetracycline derivative. The main target of tetracyclines is the bacterial ribosome[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Bacterial
References	[1]. Fuoco D. Cytotoxicity induced by tetracyclines via protein photooxidation[J]. Advances in Toxicology, et al. Cytotoxicity induced by tetracyclines via protein photooxidation[J]. Advances in Toxicology, 2015, 2015.

Density	1.72g/cm3
Boiling Point	716.4ºC at 760mmHg
Molecular Formula	C₂₂H₂₁ClN₂O₈
Molecular Weight	476.86
Flash Point	387.1ºC
Exact Mass	476.09900
PSA	181.62000
LogP	0.91580
Vapour Pressure	0mmHg at 25°C

CHEMICAL IDENTIFICATION

RTECS NUMBER :: QI7830000

CHEMICAL NAME :: 2-Naphthacenecarboxamide, 7-chloro-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octah ydro- 3,5,10,12,12a-pentahydroxy-6-methylene-1,11-dioxo-

CAS REGISTRY NUMBER :: 2013-58-3

LAST UPDATED :: 198803

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C22-H21-Cl-N2-O8

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 2 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 22,1022,1972

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 5 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 22,1022,1972

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 425 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: GICTAL Giornale Italiano di Chemioterapia. Italian Journal of Chemotherapy. (Edizioni Minerva Medica, Casella Postale 491, I-10126 Turin, Italy) V.1- 1954- Volume(issue)/page/year: 17,276,1970