362-74-3

362-74-3 structure

Name: Bucladesine
Chemical Name: Bucladesine
CAS Number: 362-74-3
Molecular Formula: C₁₈H₂₄N₅O₈P
Molecular Weight: 469.386
Catalog: Biochemical Nucleoside drugs Nucleoside intermediate
Create Date: 2018-08-26 17:00:13
Modify Date: 2024-01-03 16:33:55
Bucladesine is a cyclic nucleotide derivative which mimics the action of endogenous cAMP and is capable of permeating the cell membrane. It has vasodilator properties and is used as a cardiac stimulant. Bucladesine is a phosphodiesterase inhibitor. Bucladesine is a cell permeable cAMP analog. The compound is used in a wide variety of research applications because it mimics cAMP and can induce normal physiological responses when added to cells in experimental conditions. cAMP is only able to elicit minimal responses in these situations. The neurite outgrowth instigated by bucladesine in cell cultures has been shown to be enhanced by nardosinone.

Name	Bucladesine
Synonyms	dibutyryl cAMP Bt2 cyclic AMP (4aR,6R,7R,7aR)-6-[6-(butanoylamino)-9H-purin-9-yl]-2-hydroxy-2-oxidotetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-7-yl butanoate 3',5'-Cyclic AMP dibutyrate n-6,o-2'-dibutyryl adenosine cyclic 3':5'-monophosphate Cyclic AMP dibutyrate N-(9-b-D-Ribofuranosyl-9H-purin-6-yl)butyramide Cyclic 3',5'-(Hydrogen Phosphate) 2'-Butyrate N6,2'-O-Dibutyryl cAMP N6,2'-O-Dibutyryladenosine 3',5'-Cyclic Monophosphate Butanoic acid, (4aR,6R,7R,7aR)-tetrahydro-2-hydroxy-2-oxido-6-[6-[(1-oxobutyl)amino]-9H-purin-9-yl]-4H-furo[3,2-d]-1,3,2-dioxaphosphorin-7-yl ester N6,2'-O-dibutyryl-cAMP Bucladesine (4aR,6R,7R,7aR)-6-[6-(Butyrylamino)-9H-purin-9-yl]-2-hydroxy-2-oxidotetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-7-yl butyrate Dibutyryl cyclic 3',5'-AMP dibutyryl cyclic AMP CalciuM Dibutyacyladenosine N,O-dibutyryl cyclic AMP N-(9-beta-D-Ribofuranosyl-9H-furin-6-yl)-butyramidecyclic3',5'-(hydrogenphosphate)2'-butyrate N-(1-Oxobutyl)adenosine Cyclic 3',5'-(Hydrogen Phosphate) 2'-Butanoate Dibutyryl-cAMP Dibutyryl 3',5'-Cyclic AMP

CHEMICAL NAME :: Butyramide, N-(9-beta-D-ribofuranosyl-9H-furin-6-yl)-, cyclic 3',5'-(hydrogen phosphate) 2'- butyrate

WISWESSER LINE NOTATION :: T56 BO FOPOTJ DOV3 GQ GO C- DT56 BN DN FN HNJ IMV3

REFERENCE :: JIDEAE Journal of Investigative Dermatology. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1938- Volume(issue)/page/year: 66,313,1976