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Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Chlorquinaldol
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72-80-0

72-80-0 structure

72-80-0 structure

Name: chlorquinaldol
Chemical Name: chlorquinaldol
CAS Number: 72-80-0
Molecular Formula: C₁₀H₇Cl₂NO
Molecular Weight: 228.075
Catalog: Pharmaceutical intermediate Heterocyclic compound Quinoline compound
Create Date: 2018-06-11 20:25:06
Modify Date: 2026-07-08 13:01:05
Chlorquinaldol is a mono-hydroxyquinoline, is an antifungal and antibacterial, used for topical treatment of skin conditions and vaginal infections.

Name	chlorquinaldol
Synonyms	Intensol 5,7-Dichloro-8-hydroxyquinaldine 2-methyl-5,7-dichloro-8-hydroxyquinoline 5, 7 -D i ch 1 or o-8-qui nal di no 1 Clorquinaldol 5,7-Dichloro-2-methyl-8-hydroxyquinoline Gynotherax 5,7-Dichloro-8-hydroxyquinalidine CHLORQUINALDOL(RG) 5,7-Dichloro-8-hydroxy-2-methylquinoline Steroxin TIANFU CHEM 5,7-Dichloro-8-hydroxyquinaldine Hydroxydichloroquinaldine Siost Chlorquinaldolum CHLORQUINALDOL MFCD00023984 5,7-DICHLORO-2-METHYL-8-QUINOLINOL Siogenon Gyno-Sterosan 5,7-Dichloro-8-quinaldinol 5,7-DICHLORO-8-QUINALDOL EINECS 200-789-3 Chlorguinaldon Chloquinan Chloquinan(Chlorquinaldol) 5,7-dichloro-2-methylquinolin-8-ol 5,7-DICHLORO-8-HYDROXYQUINALDINE 5,7-DICHLORO-2-METHYLQUINOLIN-8-OL 5,7-Dichloro-8-hydroxyquinaldine ISO 9001：2015 REACH Chlorchinaldin 5,7-Dichloro-8-hydroxyquinaldine, 5,7-Dichloro-2-methylquinolin-8-ol, Chlorquinaldol Hydroxydichloroquinaldinol Siogeno 5,7-DICHLORO-8-HYDROXYQUINALIDNE Afungil Quesil Siogene 2-METHYL-5,7-DICHLORO-8-HYDROXYQUINOLINE Siogenal 5,7-Dichlor-2-methylchinolin-8-ol Saprosan Sterosan Vagisteran 5,7-dichloro-2-methyl-8-quinolino Chloroquine Impurity 4 Quinolin-8-ol, 5,7-dichloro-2-methyl Siosteran 5,7-Dichloro-2-methyl-8-quinolinol, 5,7-Dichloro-8-hydroxyquinaldine, 5,7-Dichloro-8-quinaldinol, BCM 8-Quinolinol, 5,7-dichloro-2-methyl 5,7-Dichloro-8-hydroxy-2-methylquinoline,5,7-Dichloro-2-methyl-8-quinolinol, 5,7-Dichloro-8-hydroxyquinaldine, 5,7-Dichloro-8-quinaldinol, BCM Chlorquinaldol 13CD3 5,7-Dichloro-2-methyl-8-quinolinol 5,7-Dichloro-8-hydroxyquildine Florabina 5,7-Dichloro-2-Methy Chloroquinaldol Siogen Sterozan Siasteran 2-methylchloroxine Chlorquinalol 7-Dichloro-8-hydroxy-2-methylquinoline chloroquinaldol 5,7-DICHLORO-8-QUINALDINOL Chlorchinaldol 5,7-dichloro-2-methyl-8-hydroxy-quinoline Chlorchinaldolum

Description	Chlorquinaldol is a mono-hydroxyquinoline, is an antifungal and antibacterial, used for topical treatment of skin conditions and vaginal infections.
Related Catalog	Signaling Pathways >> Anti-infection >> Bacterial Signaling Pathways >> Anti-infection >> Fungal Research Areas >> Infection

Density	1.5±0.1 g/cm3
Boiling Point	350.7±37.0 °C at 760 mmHg
Melting Point	108-112 °C (dec.)(lit.)
Molecular Formula	C₁₀H₇Cl₂NO
Molecular Weight	228.075
Flash Point	165.9±26.5 °C
Exact Mass	226.990463
PSA	33.12000
LogP	4.21
Vapour Pressure	0.0±0.8 mmHg at 25°C
Index of Refraction	1.679
Storage condition	2-8°C
Water Solubility	Insoluble

CHEMICAL IDENTIFICATION

RTECS NUMBER :: VC5600000

CHEMICAL NAME :: 8-Quinolinol, 5,7-dichloro-2-methyl-

CAS REGISTRY NUMBER :: 72-80-0

BEILSTEIN REFERENCE NO. :: 0156683

LAST UPDATED :: 199612

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C10-H7-Cl2-N-O

MOLECULAR WEIGHT :: 228.08

WISWESSER LINE NOTATION :: T66 BNJ C1 GG IG JQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 660 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Mammal - dog

DOSE/DURATION :: 2250 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 160 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :: Sex chromosome loss and nondisjunction

TEST SYSTEM :: Mold - Aspergillus nidulans

DOSE/DURATION :: 1 gm/L

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 26,159,1974

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H302
Precautionary Statements	P301 + P312 + P330
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xn:Harmful
Risk Phrases	R22;R36/37/38
Safety Phrases	S26-S36-S36/37/39
RIDADR	UN 2811 6.1/PG 3
WGK Germany	3
RTECS	VC5600000
HS Code	2933499090

21168-33-2 structure

21168-33-2

676-58-4 structure

676-58-4

~62%

72-80-0 structure

72-80-0

Literature: Organic Letters, , vol. 16, # 3 p. 864 - 867

826-81-3 structure

826-81-3

~%

72-80-0 structure

72-80-0

Literature: CH229982 , ;

Precursor 2
676-58-4 826-81-3
DownStream 0

HS Code	2933499090
Summary	2933499090. other compounds containing in the structure a quinoline or isoquinoline ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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