chlorquinaldol
chlorquinaldol structure
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Common Name | chlorquinaldol | ||
|---|---|---|---|---|
| CAS Number | 72-80-0 | Molecular Weight | 228.075 | |
| Density | 1.5±0.1 g/cm3 | Boiling Point | 350.7±37.0 °C at 760 mmHg | |
| Molecular Formula | C10H7Cl2NO | Melting Point | 108-112 °C (dec.)(lit.) | |
| MSDS | Chinese USA | Flash Point | 165.9±26.5 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
Use of chlorquinaldolChlorquinaldol is a mono-hydroxyquinoline, is an antifungal and antibacterial, used for topical treatment of skin conditions and vaginal infections. |
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | chlorquinaldol |
|---|---|
| Synonym | More Synonyms |
This table contains bioactivity, target information and biological‑assay experimental data of this compound.
| Description | Chlorquinaldol is a mono-hydroxyquinoline, is an antifungal and antibacterial, used for topical treatment of skin conditions and vaginal infections. |
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| Related Catalog |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Density | 1.5±0.1 g/cm3 |
|---|---|
| Boiling Point | 350.7±37.0 °C at 760 mmHg |
| Melting Point | 108-112 °C (dec.)(lit.) |
| Molecular Formula | C10H7Cl2NO |
| Molecular Weight | 228.075 |
| Flash Point | 165.9±26.5 °C |
| Exact Mass | 226.990463 |
| PSA | 33.12000 |
| LogP | 4.21 |
| Vapour Pressure | 0.0±0.8 mmHg at 25°C |
| Index of Refraction | 1.679 |
| InChIKey | GPTXWRGISTZRIO-UHFFFAOYSA-N |
| SMILES | Cc1ccc2c(Cl)cc(Cl)c(O)c2n1 |
| Storage condition | 2-8°C |
| Water Solubility | Insoluble |
This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.
This table summarizes toxicological test data, acute & chronic toxicity and ecological hazard parameters for this chemical.
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
MUTATION DATA
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This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H302 |
| Precautionary Statements | P301 + P312 + P330 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xn:Harmful |
| Risk Phrases | R22;R36/37/38 |
| Safety Phrases | S26-S36-S36/37/39 |
| RIDADR | UN 2811 6.1/PG 3 |
| WGK Germany | 3 |
| RTECS | VC5600000 |
| HS Code | 2933499090 |
This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.
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~62%
chlorquinaldol CAS#:72-80-0 |
| Literature: Organic Letters, , vol. 16, # 3 p. 864 - 867 |
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~%
chlorquinaldol CAS#:72-80-0 |
| Literature: CH229982 , ; |
This table lists upstream starting materials and downstream derivative products related to this chemical.
| Precursor 2 | |
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| DownStream 0 | |
This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.
| HS Code | 2933499090 |
|---|---|
| Summary | 2933499090. other compounds containing in the structure a quinoline or isoquinoline ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
This table lists relevant public references with title, journal and publication metadata for this compound.
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Purity determination of gynalgin bactericidal tablets with HPLC method.
Acta Pol. Pharm. 70(1) , 51-8, (2013) The study was aimed at developing a simple HPLC method for the determination of the content of impurities in Gynalgin, a two-component preparation. A satisfactory separation was performed on 250 x 4.6... |
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[Allergies to 8-hydroxyquinoline derivatives].
Derm. Beruf Umwelt. 36(3) , 86-90, (1988) Evaluation of our standardized test results from 1972 to 1983 indicated Vioform allergies in 1.2% of all cases and Sterosan allergies in 1.1%. Our results are within the spectrum found in the literatu... |
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In vitro activities of cloxyquin (5-chloroquinolin-8-ol) against Mycobacterium tuberculosis.
Antimicrob. Agents Chemother. 51 , 1105-6, (2007) The in vitro activities of cloxyquin (5-chloroquinolin-8-ol) against 9 standard strains and 150 clinical isolates of Mycobacterium tuberculosis were studied. The MICs ranged from 0.062 to 0.25 microg/... |
This table contains target information, in‑vitro & in‑vivo assay data for this compound.
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Name: Primary qHTS assay for inhibitors of alpha-synuclein gene (SNCA) expression
Source: NCGC
External Id: SNCA-p-activity-luciferase
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Name: Fluorescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_AG_FLUO8_1536_1X%ACT PRUN
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Name: Cytochrome P450 Family 1 Subfamily A Member 2 (CYP1A2) small molecule antagonists: lu...
Source: 824
External Id: CYP273
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Name: Fluorescence-based cell-based primary high throughput screening assay to identify pos...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_PAM_FLUO8_1536_1X%ACT PRUN
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Name: qHTS for Inhibitors of TGF-b: Cytotox Counterscreen
Source: NCGC
Target: N/A
External Id: SMAD3201
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Name: uHTS identification of cystic fibrosis induced NFkb Inhibitors in a fluoresence assay
Source: Burnham Center for Chemical Genomics
Target: cystic fibrosis transmembrane conductance regulator [Homo sapiens]
External Id: SBCCG-A764-CF-PAF-Primary-Assay
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Name: Fluorescence-based cell-based primary high throughput screening assay to identify ant...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_ANT_FLUO8_1536_1X%INH PRUN
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Name: Primary qHTS for inhibitors of NSP2Pro chikungunya virus (CHIKV)
Source: NCGC
External Id: APP-Toga-CHIKV-nsp2-p
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Name: qHTS Assay for Identifying Compounds that block Entry of Ebola Virus, Screen 2 green ...
Source: NCGC
Target: N/A
External Id: Ebola screen2_EMI141217_green
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This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.
| 5,7-Dichloro-2-methyl-8-quinolinol |
| 5,7-Dichloro-8-hydroxyquinaldine |
| 2-methyl-5,7-dichloro-8-hydroxyquinoline |
| 5,7-Dichloro-8-quinaldinol |
| Clorquinaldol |
| Chloroquinaldol |
| EINECS 200-789-3 |
| Gynotherax |
| 5,7-dichloro-2-methylquinolin-8-ol |
| 2-methylchloroxine |
| 5,7-Dichlor-2-methylchinolin-8-ol |
| Saprosan |
| Sterosan |
| 5,7-dichloro-2-methyl-8-hydroxy-quinoline |
| chlorquinaldol |
| Chlorchinaldolum |
| Chlorquinaldolum |
| MFCD00023984 |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What is the InChIKey of chlorquinaldol? |
| A: InChIKey of chlorquinaldol is GPTXWRGISTZRIO-UHFFFAOYSA-N. |
| Q: What is the boiling point of chlorquinaldol? |
| A: Boiling point of chlorquinaldol is 350.7±37.0 °C at 760 mmHg. |
| Q: What is the polar surface area (PSA) of chlorquinaldol? |
| A: Polar surface area (PSA) of chlorquinaldol is 33.12000. |
| Q: What is the English name of chlorquinaldol? |
| A: The English name of chlorquinaldol is chlorquinaldol. |
| Q: How is the water solubility of chlorquinaldol? |
| A: Water solubility of chlorquinaldol: Insoluble. |
| Q: What is the SMILES notation of chlorquinaldol? |
| A: SMILES notation of chlorquinaldol is Cc1ccc2c(Cl)cc(Cl)c(O)c2n1. |
| Q: What are the upstream materials of chlorquinaldol? |
| A: Related upstream materials(CAS) of chlorquinaldol: 676-58-4;826-81-3. |
| Q: What is the melting point of chlorquinaldol? |
| A: Melting point of chlorquinaldol is 108-112 °C (dec.)(lit.). |
| Q: What is the molecular formula of chlorquinaldol? |
| A: Molecular formula of chlorquinaldol is C10H7Cl2NO. |
| Q: What is the LogP of chlorquinaldol? |
| A: LogP of chlorquinaldol is 4.21. |
This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.
| Shanghai Nianxing Industrial Co., Ltd |
| Dayang Chem (Hangzhou) Co., Ltd. |