703-95-7

703-95-7 structure

Name: 5-Fluoroorotic acid
Chemical Name: 5-Fluoroorotic Acid
CAS Number: 703-95-7
Molecular Formula: C₅H₃FN₂O₄
Molecular Weight: 174.087
Catalog: Chemical reagent Organic reagent fatty acid
Create Date: 2018-07-09 12:15:19
Modify Date: 2024-01-02 08:40:04
5-Fluoroorotic is a selective agent in yeast molecular genetics. 5-Fluoroorotic possesses a well-expressed anticandidal effect close to that of 5-fluorocytosine, as well as moderate antidermatophytal effects[1][2].

Name	5-Fluoroorotic Acid
Synonyms	EINECS 211-876-0 5-Fluoro-6-carboxyuracil 4-Pyrimidinecarboxylic acid, 5-fluoro-1,2,3,6-tetrahydro-2,6-dioxo- 5-Fluoro orotic acid 5-Fluoro-2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid MFCD00042526 5-Fluoro-2,6-dioxo-1,2,3,6-tetrahydro-4-pyrimidinecarboxylic acid Orotic acid, 5-fluoro- 5-Fluoroorotic acid 5-Fluoroorotic acid monohydrate

Description	5-Fluoroorotic is a selective agent in yeast molecular genetics. 5-Fluoroorotic possesses a well-expressed anticandidal effect close to that of 5-fluorocytosine, as well as moderate antidermatophytal effects[1][2].
Related Catalog	Research Areas >> Cancer Research Areas >> Infection Signaling Pathways >> Others >> Others
References	[1]. Boeke JD, et, al. 5-Fluoroorotic acid as a selective agent in yeast molecular genetics. Methods Enzymol. 1987; 154: 164-75. [2]. Nikolova K, et, al. Studies on the antimycotic activity of 5-fluoroorotic acid. Methods Find Exp Clin Pharmacol. 1987 Feb; 9(2): 85-9.

Density	1.8±0.1 g/cm3
Melting Point	278 °C (dec.)(lit.)
Molecular Formula	C₅H₃FN₂O₄
Molecular Weight	174.087
Exact Mass	174.007690
PSA	103.02000
LogP	-1.00
Index of Refraction	1.580
Storage condition	−20°C
Water Solubility	NH4OH 4 M: 50 mg/mL, clear, faintly yellow

CHEMICAL NAME :: 4-Pyrimidinecarboxylic acid, 1,2,3,6-tetrahydro-2,6-dioxo-5-fluoro-

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ADTEAS Advances in Teratology. (New York, NY) V.1-5, 1966-72. Discontinued. Volume(issue)/page/year: 3,181,1968

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NCISP* National Cancer Institute Screening Program Data Summary, Developmental Therapeutics Program. (Bethesda, MD 20205) Volume(issue)/page/year: JAN1986 *** REVIEWS *** TOXICOLOGY REVIEW 32XPAD "Teratology," Berry, C.L., and D.E. Poswillo, eds., New York, Springer, 1975 Volume(issue)/page/year: -,49,1975

HS Code	2933599090
Summary	2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%