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16502-01-5

16502-01-5 structure
16502-01-5 structure
  • Name: Tryptoline
  • Chemical Name: 1,2,3,4-tetrahydro-9h-pyrido[3,4-b]indole
  • CAS Number: 16502-01-5
  • Molecular Formula: C11H12N2
  • Molecular Weight: 172.226
  • Catalog: Signaling Pathways GPCR/G Protein 5-HT Receptor
  • Create Date: 2018-12-28 09:28:08
  • Modify Date: 2024-01-01 19:54:04
  • Tetrahydro-β-carboline (Tryptoline) is a metabolite of tryptamine, also is a competitive serotonin reuptake inhibitor with an Ki value of 6.1 µM[1].

Name 1,2,3,4-tetrahydro-9h-pyrido[3,4-b]indole
Synonyms 2,3,4,9-Tetrahydro-1H-β-carboline
Tetrahydro-b-carboline
Tetrahydro-β-carboline
1,2,3,4-Tetrahydro-b-carboline
2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole
1H-Pyrido[3,4-b]indole, 2,3,4,9-tetrahydro-
MFCD00004954
1,2,3,4-Tetrahydro-9H-Pyrido[3,4-B]Indole
Tetrahydro-beta-carboline
Triptoline
Tryptoline
Description Tetrahydro-β-carboline (Tryptoline) is a metabolite of tryptamine, also is a competitive serotonin reuptake inhibitor with an Ki value of 6.1 µM[1].
Related Catalog
Target

serotonin:6.1 μM (Ki)

In Vivo Tetrahydro-β-carboline (20 µg; i.c.v.) increases the serotonin levels in the same part of the brain in rats[1]. Animal Model: 180-200g female Sprague-Dawley rats[1] Dosage: 20 µg Administration: Intraventricular injection Result: Increased of serotonin levels in the same part of the brain whereas the monoamine oxidase activity was not altered.
Density 1.2±0.1 g/cm3
Boiling Point 351.6±32.0 °C at 760 mmHg
Melting Point 206-208 °C(lit.)
Molecular Formula C11H12N2
Molecular Weight 172.226
Flash Point 166.5±25.1 °C
Exact Mass 172.100052
PSA 27.82000
LogP 1.33
Vapour Pressure 0.0±0.8 mmHg at 25°C
Index of Refraction 1.670
Storage condition Refrigerator
Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi: Irritant;
Risk Phrases R36/37/38
Safety Phrases S26-S36
RIDADR NONH for all modes of transport
WGK Germany 3
HS Code 2933990090
HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%