Name | 1,2,3,4-tetrahydro-9h-pyrido[3,4-b]indole |
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Synonyms |
2,3,4,9-Tetrahydro-1H-β-carboline
Tetrahydro-b-carboline Tetrahydro-β-carboline 1,2,3,4-Tetrahydro-b-carboline 2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole 1H-Pyrido[3,4-b]indole, 2,3,4,9-tetrahydro- MFCD00004954 1,2,3,4-Tetrahydro-9H-Pyrido[3,4-B]Indole Tetrahydro-beta-carboline Triptoline Tryptoline |
Description | Tetrahydro-β-carboline (Tryptoline) is a metabolite of tryptamine, also is a competitive serotonin reuptake inhibitor with an Ki value of 6.1 µM[1]. |
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Related Catalog | |
Target |
serotonin:6.1 μM (Ki) |
In Vivo | Tetrahydro-β-carboline (20 µg; i.c.v.) increases the serotonin levels in the same part of the brain in rats[1]. Animal Model: 180-200g female Sprague-Dawley rats[1] Dosage: 20 µg Administration: Intraventricular injection Result: Increased of serotonin levels in the same part of the brain whereas the monoamine oxidase activity was not altered. |
Density | 1.2±0.1 g/cm3 |
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Boiling Point | 351.6±32.0 °C at 760 mmHg |
Melting Point | 206-208 °C(lit.) |
Molecular Formula | C11H12N2 |
Molecular Weight | 172.226 |
Flash Point | 166.5±25.1 °C |
Exact Mass | 172.100052 |
PSA | 27.82000 |
LogP | 1.33 |
Vapour Pressure | 0.0±0.8 mmHg at 25°C |
Index of Refraction | 1.670 |
Storage condition | Refrigerator |
Symbol |
GHS07 |
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Signal Word | Warning |
Hazard Statements | H315-H319-H335 |
Precautionary Statements | P261-P305 + P351 + P338 |
Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
Hazard Codes | Xi: Irritant; |
Risk Phrases | R36/37/38 |
Safety Phrases | S26-S36 |
RIDADR | NONH for all modes of transport |
WGK Germany | 3 |
HS Code | 2933990090 |
Precursor 9 | |
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DownStream 10 | |
HS Code | 2933990090 |
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Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |