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527-73-1

527-73-1 structure
527-73-1 structure
  • Name: 2-Nitroimidazole
  • Chemical Name: 2-nitroimidazole
  • CAS Number: 527-73-1
  • Molecular Formula: C3H3N3O2
  • Molecular Weight: 113.075
  • Catalog: Signaling Pathways Anti-infection Bacterial
  • Create Date: 2018-06-21 18:41:25
  • Modify Date: 2024-01-02 15:09:39
  • Azomycin is an antibiotic which can be active against aerobic Gram-positive and Gram-negative bacteria.

Name 2-nitroimidazole
Synonyms 2-Nitroimidazol
Azomycin
2-Nitro-1H-imidazole
MFCD00005185
2-Nitroimidazole
EINECS 208-425-5
1H-Imidazole, 2-nitro-
Description Azomycin is an antibiotic which can be active against aerobic Gram-positive and Gram-negative bacteria.
Related Catalog
Target

Bacterial[1]

In Vitro Azomycin is an antibiotic which can be active against aerobic Gram-positive and Gram-negative bacteria. It is found that Azomycin is also active against a variety of anaerobic bacteria[1].
References

[1]. Shoji JH, et al. Isolation of azomycin from Pseudomonas fluorescens. J Antibiot (Tokyo). 1989 Oct;42(10):1513-4.

Density 1.6±0.1 g/cm3
Boiling Point 373.6±25.0 °C at 760 mmHg
Melting Point 287 °C (dec.)(lit.)
Molecular Formula C3H3N3O2
Molecular Weight 113.075
Flash Point 179.7±23.2 °C
Exact Mass 113.022530
PSA 74.50000
LogP 0.15
Vapour Pressure 0.0±0.8 mmHg at 25°C
Index of Refraction 1.612
Storage condition Refrigerator
Water Solubility insoluble

CHEMICAL IDENTIFICATION

RTECS NUMBER :
NI7875000
CHEMICAL NAME :
Imidazole, 2-nitro-
CAS REGISTRY NUMBER :
527-73-1
BEILSTEIN REFERENCE NO. :
0116444
LAST UPDATED :
199701
DATA ITEMS CITED :
9
MOLECULAR FORMULA :
C3-H3-N3-O2
MOLECULAR WEIGHT :
113.09
WISWESSER LINE NOTATION :
T5M CNJ BNW

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
316 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
80 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
316 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
80 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :
Mutation in microorganisms
TEST SYSTEM :
Microorganism - not otherwise specified
DOSE/DURATION :
1 mg/plate
REFERENCE :
JGAMA9 Journal of General and Applied Microbiology. (Microbiology Research Foundation, c/o Japan Academic Soc. Center Bldg., 2-4-16 Yayoi, Bunkyo-ku, Tokyo, 113, Japan) V.1- 1955- Volume(issue)/page/year: 11,129,1965 *** REVIEWS *** TOXICOLOGY REVIEW ADCMAZ Advances in Chemotherapy. (New York, NY) V.1-3, 1964-68. For publisher information, see AVPCAQ. Volume(issue)/page/year: 3,39,1968 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X6614 No. of Facilities: 7 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 1822 (estimated) No. of Female Employees: 272 (estimated)
Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H302-H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Faceshields;Gloves
Hazard Codes Xn:Harmful
Risk Phrases R22;R36/37/38
Safety Phrases S26-S36
RIDADR UN 2811 6.1/PG 3
WGK Germany 3
RTECS NI7875000
Packaging Group III
Hazard Class 6.1
HS Code 2933990090
HS Code 2933290090
Summary 2933290090. other compounds containing an unfused imidazole ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%