111555-58-9

111555-58-9 structure

Name: NALTRIBEN MESYLATE
Chemical Name: Naltriben
CAS Number: 111555-58-9
Molecular Formula: C₂₆H₂₅NO₄
Molecular Weight: 415.48
Catalog: Signaling Pathways GPCR/G Protein Opioid Receptor
Create Date: 2017-01-01 06:25:55
Modify Date: 2026-07-08 15:21:45
Naltriben is a selective δ2-opioid receptor antagonist and TRPM7 activator. Naltriben enhances glioblastoma cell migration and invasion. Naltriben can be used in research into neurological diseases and cancer[1][2].

Name	Naltriben
Synonyms	17-(Cyclopropylmethyl)-6,7-didehydro-,5alpha-oxy-14beta-dihydroxy-6,',3'-benzo[b]furanomorphinan mesylate NALTRIBEN METHANESULFONATE C26H25NO4 17-(Cyclopropylmethyl)-6,7-didehydro-3,14β-dihydroxy-4,5α-oxy-6,',3'-benzo[b]furanomorphinanmesylate 17-(Cyclopropylmethyl)-6,7-didehydro-3,14b-dihydroxy-4,5a-oxy-6,',3'-benzo[b]furanomorphinanmesylate naltrindolebenzofuran 17-(CYCLOPROPYLMETHYL)-6,7-DIDEHYDRO-3, 14B-DIHYDROXY-4,5A-OXY-6,',3'-BENZO[B]FURANOMORPHINAN MESYLATE 4,8-Methano-8aH-bisbenzofuro[3,2-e:2',3'-g]isoquinoline-1,8a-diol, 7-(cyclopropylmethyl)-5,6,7,8,9,14b-hexahydro-, (4bS,8R,8aS,14bR) NTB naltrindole benzofuran HMS2089G18

Description	Naltriben is a selective δ2-opioid receptor antagonist and TRPM7 activator. Naltriben enhances glioblastoma cell migration and invasion. Naltriben can be used in research into neurological diseases and cancer[1][2].
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> TRP Channel Research Areas >> Cancer Signaling Pathways >> GPCR/G Protein >> Opioid Receptor Signaling Pathways >> Neuronal Signaling >> Opioid Receptor
References	[1]. Lever JR, et al. Selective in vivo binding of [3H]naltriben to delta-opioid receptors in mouse brain. Eur J Pharmacol. 1998 Jun 5;350(2-3):335-44. [2]. Wong R, et al. Activation of TRPM7 by naltriben enhances migration and invasion of glioblastoma cells. Oncotarget. 2017 Feb 14;8(7):11239-11248.

16676-29-2

6092-80-4

~81%

111555-58-9

Literature: Portoghese; Sultana; Nagase; Takemori Journal of Medicinal Chemistry, 1988 , vol. 31, # 2 p. 281 - 282

122517-78-6

111555-58-9

Literature: PROGENICS PHARMACEUTICALS, INC Patent: WO2009/67275 A1, 2009 ; Location in patent: Page/Page column 140-141 ; WO 2009/067275 A2

Precursor 3
16676-29-2 6092-80-4 122517-78-6
DownStream 0