40252-74-2
40252-74-2 structure
- Name: DMeOB
- Chemical Name: (E)-1-(3-methoxyphenyl)-N-[(E)-(3-methoxyphenyl)methylideneamino]methanimine
- CAS Number: 40252-74-2
- Molecular Formula: C16H16N2O2
- Molecular Weight: 268.31
- Catalog: Signaling Pathways GPCR/G Protein mGluR
- Create Date: 2017-01-21 08:11:17
- Modify Date: 2025-09-06 15:52:25
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DMeOB is an agonist of mGluR5 receptor with an IC50 of 3 μM. DMeOB has a negative modulatory effect[1].
| Name | (E)-1-(3-methoxyphenyl)-N-[(E)-(3-methoxyphenyl)methylideneamino]methanimine |
|---|---|
| Synonyms |
3,3'-dimethoxybenzalazine
DMeOB m-anisaldehyde azine 3,3'-dimethoxybenzaldazine 3-Methoxybenzaldehyde [(3-methoxyphenyl)methylene]hydrazone 3-methoxybenzaldehyde azine |
| Description | DMeOB is an agonist of mGluR5 receptor with an IC50 of 3 μM. DMeOB has a negative modulatory effect[1]. |
|---|---|
| Related Catalog | |
| References |
| Density | 1.05g/cm3 |
|---|---|
| Boiling Point | 438.2ºC at 760mmHg |
| Molecular Formula | C16H16N2O2 |
| Molecular Weight | 268.31 |
| Flash Point | 176.1ºC |
| Exact Mass | 268.12100 |
| PSA | 43.18000 |
| LogP | 3.15680 |
| Index of Refraction | 1.54 |
| Storage condition | 2-8°C |
| Symbol |
GHS05, GHS09 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H318-H400 |
| Precautionary Statements | P273-P280-P305 + P351 + P338 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xi: Irritant;N: Dangerous for the environment; |
| Risk Phrases | 41-50/53 |
| Safety Phrases | 26-36/37/39-60-61 |
| RIDADR | UN 3077 9/PG 3 |
|
~80%
40252-74-2 |
| Literature: O'Brien, Julie A.; Lemaire, Wei; Chen, Tsing-Bau; Chang, Raymond S. L.; Jacobson, Marlene A.; Ha, Sookhee N.; Lindsley, Craig W.; Schaffhauser, Herve J.; Sur, Cyrille; Pettibone, Douglas J.; Conn, P. Jeffrey; Williams Jr., David L. Molecular Pharmacology, 2003 , vol. 64, # 3 p. 731 - 740 |
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~%
40252-74-2 |
| Literature: Pietra; Trinchera Gazzetta Chimica Italiana, 1956 , vol. 86, p. 1045,1050 |
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~%
40252-74-2
Detail
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| Literature: Tomioka, Hideo; Tabayashi, Kazuo; Ozaki, Yasuji; Izawa, Yasuji Tetrahedron, 1985 , vol. 41, # 8 p. 1435 - 1440 |
