- DC Chemicals Limited
- China
- Product Name: Rebeprazole sodium
- Price: $300.0/1g
- Purity: 98.0%
- Stocking Period: 3 Day
- Contact: Tony Cao
- Dayang Chem (Hangzhou) Co., Ltd.
- China
- Product Name: RABEPRAZOLE SODIUM
- Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
- Purity: 98.0%
- Stocking Period: Inquiry
- Contact: Ms Wang
- Zhejiang Hangyu API Co., Ltd
- China
- Product Name: Rebeprazole sodium
- Price: ￥Inquiry/1kg
- Purity: 99.5%
- Stocking Period: Inquiry
- Contact: Vinnie
- Henan Tianfu Chemical Co., Ltd.
- China
- Product Name: Rabeprazole sodium
- Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
- Purity: 99.0%
- Stocking Period: Inquiry
- Contact: Anson
117976-90-6
117976-90-6 structure
- Name: Rabeprazole sodium
- Chemical Name: rabeprazole sodium
- CAS Number: 117976-90-6
- Molecular Formula: C18H20N3NaO3S
- Molecular Weight: 381.424
- Catalog: API Digestive system medication Acid and gastric mucosal protective drugs
- Create Date: 2018-04-22 08:00:00
- Modify Date: 2024-01-02 04:00:34
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Rabeprazole sodium(LY307640 sodium) is an antiulcer drug in the class of proton pump inhibitors.Target: Proton PumpRabeprazole belongs to a class of antisecretory compounds (substituted benzimidazole proton-pump inhibitors) that do not exhibit anticholinergic or histamine H2-receptor antagonist properties, but suppress gastric acid secretion by inhibiting the gastric H+/K+ATPase (hydrogen-potassium adenosine triphosphatase) at the secretory surface of the gastric parietal cell. Because this enzyme is regarded as the acid (proton) pump within the parietal cell, rabeprazole has been characterized as a gastric proton-pump inhibitor. Rabeprazole blocks the final step of gastric acid secretion. In gastric parietal cells, rabeprazole is protonated, accumulates, and is transformed to an active sulfenamide. When studied in vitro, rabeprazole is chemically activated at pH 1.2 with a half-life of 78 seconds.
| Name | rabeprazole sodium |
|---|---|
| Synonyms |
natrium-2-({[4-(3-methoxypropoxy)-3-methylpyridin-2-yl]methyl}sulfinyl)benzimidazol-1-id
Sodium 2-({[4-(3-methoxypropoxy)-3-methyl-2-pyridinyl]methyl}sulfinyl)benzimidazol-1-ide 1H-Benzimidazole, 2-[[[4-(3-methoxypropoxy)-3-methyl-2-pyridinyl]methyl]sulfinyl]-, sodium salt (1:1) RABEPRAZOLE NA sodium,2-[[4-(3-methoxypropoxy)-3-methylpyridin-2-yl]methylsulfinyl]benzimidazol-1-ide sodium 2-{[4-(3-methoxypropoxy)-3-methylpyridin-2-yl]methanesulfinyl}-1H-benzimidazol-1-ide Pariet Zechin Rabonik sodium 2-({[4-(3-methoxypropoxy)-3-methylpyridin-2-yl]methyl}sulfinyl)benzimidazol-1-ide Rebeprazole sodium Aciphex Rabeprazole Sodium Salt Rabeprazole sodium 2-([4-(3-Methoxypropoxy)-3-methylpyridin-2-yl]methylsulfinyl)-1H-benzo[d]imidazole,Pariprazole Sodium rabeprazole Rabeprazole (sodium) |
| Description | Rabeprazole sodium(LY307640 sodium) is an antiulcer drug in the class of proton pump inhibitors.Target: Proton PumpRabeprazole belongs to a class of antisecretory compounds (substituted benzimidazole proton-pump inhibitors) that do not exhibit anticholinergic or histamine H2-receptor antagonist properties, but suppress gastric acid secretion by inhibiting the gastric H+/K+ATPase (hydrogen-potassium adenosine triphosphatase) at the secretory surface of the gastric parietal cell. Because this enzyme is regarded as the acid (proton) pump within the parietal cell, rabeprazole has been characterized as a gastric proton-pump inhibitor. Rabeprazole blocks the final step of gastric acid secretion. In gastric parietal cells, rabeprazole is protonated, accumulates, and is transformed to an active sulfenamide. When studied in vitro, rabeprazole is chemically activated at pH 1.2 with a half-life of 78 seconds. |
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| Related Catalog | |
| References |
| Density | 0.45~0.55 g/ml |
|---|---|
| Boiling Point | 603.9ºC at 760 mmHg |
| Melting Point | 140-141ºC dec. |
| Molecular Formula | C18H20N3NaO3S |
| Molecular Weight | 381.424 |
| Flash Point | 319.1ºC |
| Exact Mass | 381.112305 |
| PSA | 93.41000 |
| LogP | 3.48420 |
| Storage condition | Hygroscopic, -20°C Freezer, Under Inert Atmosphere |
| Water Solubility | H2O: soluble10mg/mL (clear solution) |
| RIDADR | NONH for all modes of transport |
|---|---|
| HS Code | 2933399090 |
|
~97%
117976-90-6 |
| Literature: US2007/225502 A1, ; Page/Page column 5 ; |
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~%
117976-90-6 |
| Literature: WO2004/63188 A1, ; Page 13 ; |
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~%
117976-90-6 |
| Literature: WO2008/45777 A2, ; Page/Page column 32 ; |
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~%
117976-90-6 |
| Literature: WO2008/146297 A2, ; Page/Page column 6 ; |
| Precursor 2 | |
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| DownStream 0 | |
| HS Code | 2933399090 |
|---|---|
| Summary | 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |