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610-88-8

610-88-8 structure
610-88-8 structure
  • Name: Tenuazonic acid-(Copper salt)
  • Chemical Name: Tenuazonic Acid
  • CAS Number: 610-88-8
  • Molecular Formula: C10H15NO3
  • Molecular Weight: 197.231
  • Catalog: analytical chemistry Standard Food and cosmetics standards
  • Create Date: 2018-04-25 08:00:00
  • Modify Date: 2025-08-20 18:00:54
  • Tenuazonic acid, belonging to tetramic acids that are the largest family of natural products, is a putative nonhost-selective mycotoxin isolated from Alternaria alternate[1]. Tenuazonic acid blocks electron transport beyond primary quinone acceptor (QA) by interacting with D1 protein and it is a broad-spectrum and effective photosystem II (PSII) inhibitor[2].
Name Tenuazonic Acid
Synonyms 3-acetyl-5-(butan-2-yl)-4-hydroxy-1,5-dihydro-2H-pyrrol-2-one
3-Acetyl-5-sec-butyl-4-hydroxy-1,5-dihydro-2H-pyrrol-2-one
4-acetyl-2-butan-2-yl-3-hydroxy-1,2-dihydropyrrol-5-one
2H-Pyrrol-2-one, 3-acetyl-1,5-dihydro-4-hydroxy-5-(1-methylpropyl)-
Description Tenuazonic acid, belonging to tetramic acids that are the largest family of natural products, is a putative nonhost-selective mycotoxin isolated from Alternaria alternate[1]. Tenuazonic acid blocks electron transport beyond primary quinone acceptor (QA) by interacting with D1 protein and it is a broad-spectrum and effective photosystem II (PSII) inhibitor[2].
Related Catalog
Target

PSII[2]

References

[1]. Zhou B, et al. An evaluation of tenuazonic acid, a potential biobased herbicide in cotton. Pest Manag Sci. 2019 Mar 7.

[2]. Chen S, et al. Recent advances in tenuazonic acid as a potential herbicide. Pestic Biochem Physiol. 2017 Nov;143:252-257.
Density 1.2±0.1 g/cm3
Boiling Point 401.1±45.0 °C at 760 mmHg
Melting Point 74.5°C
Molecular Formula C10H15NO3
Molecular Weight 197.231
Flash Point 196.4±28.7 °C
Exact Mass 197.105194
PSA 66.40000
LogP 0.81
Vapour Pressure 0.0±2.1 mmHg at 25°C
Index of Refraction 1.519
Storage condition -20°C

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UY7425000
CHEMICAL NAME :
3-Pyrrolin-2-one, 3-acetyl-5-sec-butyl-4-hydroxy-, L-
CAS REGISTRY NUMBER :
610-88-8
LAST UPDATED :
199709
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C10-H15-N-O3
MOLECULAR WEIGHT :
197.26
WISWESSER LINE NOTATION :
T5MV EHJ CV1 DQ EY2&1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
225 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
85GDA2 "CRC Handbook of Antibiotic Compounds," Vols.1- , Berdy, J., Boca Raton, FL, CRC Press, 1980- Volume(issue)/page/year: 5,65,1981
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
81 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
EVHPAZ EHP, Environmental Health Perspectives. (U.S. Government Printing Office, Supt of Documents, Washington, DC 20402) No.1- 1972- Volume(issue)/page/year: 4,87,1973
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
145 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
85GDA2 "CRC Handbook of Antibiotic Compounds," Vols.1- , Berdy, J., Boca Raton, FL, CRC Press, 1980- Volume(issue)/page/year: 5,65,1981
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
125 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
85GDA2 "CRC Handbook of Antibiotic Compounds," Vols.1- , Berdy, J., Boca Raton, FL, CRC Press, 1980- Volume(issue)/page/year: 5,65,1981
Symbol GHS06
GHS06
Signal Word Danger
Hazard Statements H301
Precautionary Statements P301 + P310
Hazard Codes Xn
Risk Phrases 22
RIDADR UN 2811 6.1/PG 3
WGK Germany 3
RTECS UY7425000
Packaging Group III
Hazard Class 6.1(b)
HS Code 2933990090
921-74-4 structure

921-74-4

~%

610-88-8 structure

610-88-8

Literature: Matsuo; Kitaguchi; Takata; Tanaka Chemical and Pharmaceutical Bulletin, 1980 , vol. 28, # 8 p. 2494 - 2502
18598-74-8 structure

18598-74-8

~%

610-88-8 structure

610-88-8

Literature: Poncet, Joel; Jouin, Patrick; Castro, Bertrand; Nicolas, Louisette; Boutar, Mohamed; Gaudemer, Alain Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1990 , p. 611 - 616
62972-98-9 structure

62972-98-9

~%

610-88-8 structure

610-88-8

36576-19-9 structure

36576-19-9

Literature: Poncet, Joel; Jouin, Patrick; Castro, Bertrand; Nicolas, Louisette; Boutar, Mohamed; Gaudemer, Alain Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1990 , p. 611 - 616
Precursor  3

DownStream  0

HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
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