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6681-18-1

6681-18-1 structure
6681-18-1 structure
  • Name: (+)-Magnoflorine chloride
  • Chemical Name: Magnoflorine chloride
  • CAS Number: 6681-18-1
  • Molecular Formula: C20H24ClNO4
  • Molecular Weight: 377.862
  • Catalog: Signaling Pathways Anti-infection Fungal
  • Create Date: 2018-10-04 10:53:23
  • Modify Date: 2024-01-02 08:34:14
  • Magnoflorine chloride (Magnoflorine chloride), an aporphine alkaloid found in Acoruscalamus, reduces the formation of C. albicans biofilm[1]. Magnoflorine chloride has anti-fungal, anti-antidiabetic and anti-oxidative activity[2].
Name Magnoflorine chloride
Synonyms Corytuberine methochloride
Magnoflorine chloride
1,11-dihydroxy-10-methoxynaphthacene-5,12-dione
(6aS)-1,11-Dihydroxy-2,10-dimethoxy-6,6-dimethyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolinium chloride
4H-Dibenzo[de,g]quinolinium, 5,6,6a,7-tetrahydro-1,11-dihydroxy-2,10-dimethoxy-6,6-dimethyl-, chloride, (6aS)- (1:1)
5,12-Naphthacenedione,1,11-dihydroxy-10-methoxy
Thalictrine chloride
Description Magnoflorine chloride (Magnoflorine chloride), an aporphine alkaloid found in Acoruscalamus, reduces the formation of C. albicans biofilm[1]. Magnoflorine chloride has anti-fungal, anti-antidiabetic and anti-oxidative activity[2].
Related Catalog
References

[1]. Kim J, et al. Antifungal activity of magnoflorine against Candida strains. World J Microbiol Biotechnol. 2018 Oct 31;34(11):167.

[2]. Haque MA, et al. Magnoflorine Enhances LPS-Activated Pro-Inflammatory Responses via MyD88-Dependent Pathways in U937 Macrophages. Planta Med. 2018 Nov;84(17):1255-1264.
Molecular Formula C20H24ClNO4
Molecular Weight 377.862
Exact Mass 377.139374
PSA 58.92000
Storage condition 2-8°C

CHEMICAL IDENTIFICATION

RTECS NUMBER :
CE0970000
CHEMICAL NAME :
6a-alpha-Aporphinium, 1,11-dihydroxy-2,10-dimethoxy-6-methyl-, chloride
CAS REGISTRY NUMBER :
6681-18-1
LAST UPDATED :
198406
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C20-H24-N-O4.Cl

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
19600 ug/kg
TOXIC EFFECTS :
Peripheral Nerve and Sensation - flaccid paralysis without anesthesia (usually neuromuscular blockage) Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - other changes
REFERENCE :
JJPAAZ Japanese Journal of Pharmacology. (Japanese Pharmacological Soc., c/o Dept. of Pharmacology, Faculty of Medicine, Kyoto Univ., Sakyo-ku, Kyoto 606, Japan) V.1- 1951- Volume(issue)/page/year: 7,135,1958
Precursor  0

DownStream  1


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title: CAS No. 6681-18-1 | Chemsrc address: https://m.chemsrc.com/en/baike/589512.html

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