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4488-22-6

4488-22-6 structure
4488-22-6 structure
Name [1,1'-Binaphthalene]-2,2'-diamine
Synonyms diamine (HPLC)
(±)-2,2'-Diamino-1,1'-binaphthalene
1,1-BINAPHY1-2,2'-DIAMINE
1-(1-Naphtyl)naphthalen-2-amine
2,2′-Diamino-1,1′-binaphthyl(Binam)
RACEMIC-2,2'-DIAMINO-1,1'-BINAPHTHYL, MIN
(R)-(+)-1,1'-binaphthyl-2,2'-diamine
R(+)-DABN
BINAM
(+/-)-1,1'-BINAPHTHALENE-2,2'-DIAMINE
R(+)-1,1'-BINAPHTHALENE-2,2'-DIAMINE
1,1'-Bi[naphthalene-2-amine]
(R)-(+)-2,2'-DIAMINO-1,1'-BINAPHTHYL
tianfu-chem_[1,1'-Binaphthalene]-2,2'-diamine 4-6
(+)-2,2'-diamino-1,1-binaphthyl
(+/-)-2,2'-Diamino-1,1'-binaphthyl
(+/-)-2,2'-DIAMINO-1,1'-BINAPHTHYL
1,1'-Bi(2-naphthalenamine)
(+)(R)-2,2'-diamino-1,1'-binaphthyl
RACEMIC-2,2'-DIAMINO-1,1'-BINAPHTHYL
2,2'-diamino-1,1'-binaphthalene
(±)-1,1'-Bi(2-naphthylamine)
1,1'-Binaphthalene-2,2'-diamine
(+/-)-2,2'-DIAMINO-1,1'-BINAPHTHALENE
(S)-1,1'-binaphthyl-2,2'-diamine
1,1'-Bi(naphthalene-2-amine)
1,1'-Bi[2-naphthalenamine]
binaphthyldiamine
racemic-2,2'-Diamino-1,1'-binaphthyl,min
rac-1,1'-binaphthyl-2,2'-diamine
MFCD00145204
1,1'-Binaphthyl-2,2'-diamine >
S(-)-DABN
2,2-DIAMINO-1,1'-BINAPHTHALENE
(S)-(-)-1,1'-BINAPHTHYL-2,2'-DIAMINE ISO 9001：2015 REACH
1,1'-Binaphthalene]-2,2'-diamine
[[(3-Hydroxytricyclo[3.3.1.13,7]dec-1-yl)imino]bis(1-oxo-2,1-ethanediyl)]bis-2-pyrrolidinecbonitrile
(S)-(-)-2,2'-DIAMINO-1,1'-BINAPHTHYL
(+/-) -rac-2,2'-Diamino-1,1'-binaphthalene
1,1-BINAPHY,2'-DIAMINE
1,1'-Binaphthyl-2,2'-diamine
S(-)-1,1'-BINAPHTHALENE-2,2'-DIAMINE
Description 1,1'-Binaphthyl-2,2'-diamine is the inactive isomer of (S)-[1,1'-Binaphthalene]-2,2'-diamine (HY-W007978A), and can be used as an experimental control. (S)-[1,1'-Binaphthalene]-2,2'-diamine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
Related Catalog
References

[1]. Kettle JG, et al. Discovery of AZD4625, a Covalent Allosteric Inhibitor of the Mutant GTPase KRASG12C. J Med Chem. 2022 May 12;65(9):6940-6952.  

Density 1.3±0.1 g/cm3
Boiling Point 480.8±30.0 °C at 760 mmHg
Melting Point 242-244ºC(lit.)
Molecular Formula C20H16N2
Molecular Weight 284.35
Flash Point 293.9±24.0 °C
Exact Mass 284.131348
PSA 52.04000
LogP 3.85
Appearance slightly beige
Vapour Pressure 0.0±1.2 mmHg at 25°C
Index of Refraction 1.775
Water Solubility Insoluble in water

CHEMICAL IDENTIFICATION

RTECS NUMBER :
DU3090000
CHEMICAL NAME :
(1,1'-Binaphthalene)-2,2'-diamine
CAS REGISTRY NUMBER :
4488-22-6
BEILSTEIN REFERENCE NO. :
2138401
LAST UPDATED :
199612
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C20-H16-N2
MOLECULAR WEIGHT :
284.38
WISWESSER LINE NOTATION :
L66J CZ B- 2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
590 mg/kg/25W-I
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Liver - tumors
REFERENCE :
AJCAA7 American Journal of Cancer. (New York, NY) V.15-40, 1931-40. For publisher information, see CNREA8. Volume(issue)/page/year: 40,62,1940
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
2700 mg/kg/27W-I
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Liver - tumors
REFERENCE :
AJCAA7 American Journal of Cancer. (New York, NY) V.15-40, 1931-40. For publisher information, see CNREA8. Volume(issue)/page/year: 40,62,1940
Symbol GHS05 GHS07
GHS05, GHS07
Signal Word Danger
Hazard Statements H302-H318
Precautionary Statements P280-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xn
Risk Phrases 36/37/38-41-22
Safety Phrases S26;S39
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS DU3090000
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