51219-88-6

51219-88-6 structure
51219-88-6 structure

Name tetramethylene-d8 sulfone
Synonyms Sulfolane-d8
MFCD00148960
Description 1,1-Dioxothiolan-d8 is the deuterium labeled 1,1-Dioxothiolan[1].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

Boiling Point 283-285ºC
Melting Point 25-27ºC
Molecular Formula C4D8O2S
Molecular Weight 128.21900
Flash Point 177ºC
Exact Mass 128.07500
PSA 42.52000
LogP 1.27580
Hazard Codes Xn
Risk Phrases R22
Safety Phrases S25