51276-47-2
51276-47-2 structure
- Name: Glufosinate
- Chemical Name: phosphinothricin
- CAS Number: 51276-47-2
- Molecular Formula: C5H12NO4P
- Molecular Weight: 181.12700
- Catalog: Research Areas Neurological Disease
- Create Date: 2018-03-17 08:00:00
- Modify Date: 2024-01-04 13:09:01
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Glufosinate, a phosphinic acid analogue of glutamic acid, is a herbicide which is converted by plant cells into PT (L-phosphinothricin). Glufosinate exerts neurotoxic activity[1][2].
| Name | phosphinothricin |
|---|---|
| Synonyms |
2-amino-4-(hydroxymethylphosphinyl)butyric acid
(2RS)-2-amino-4-[hydroxy(methyl)phosphinoyl]butyric acid 4-[hydroxy(methyl)phosphinoyl]-DL-homoalanine 2-amino-4-(hydroxymethylphosphinyl)butanoic acid glufosinate |
| Description | Glufosinate, a phosphinic acid analogue of glutamic acid, is a herbicide which is converted by plant cells into PT (L-phosphinothricin). Glufosinate exerts neurotoxic activity[1][2]. |
|---|---|
| Related Catalog | |
| In Vitro | Glufosinate (1-100 μM; 12DIV) disrupts cell-cell adhesion in differentiated V-SVZ neural stem cells (NSCs)[2]. Glufosinate (1-100 μM; 12DIV) significantly decreases Celsr2 gene expression at 100 μM[2]. Glufosinate impairs ependymal cell capability to synthetize cilia[2]. |
| In Vivo | Glufosinate (10-250 mg/kg; gavage; Daily; on days 6-15 of gestation) indicates maternal toxicity in the groups given 50 or 250 mg/kg in Wistar rats[3]. The Elimination of Glufosinate (oral intubation) in the blood takes place with a half-life of less than 4 hours in male and female rats[3]. |
| References |
| Density | 1.378 g/cm3 |
|---|---|
| Boiling Point | 519.1ºC at 760 mmHg |
| Melting Point | 230ºC |
| Molecular Formula | C5H12NO4P |
| Molecular Weight | 181.12700 |
| Flash Point | 267.7ºC |
| Exact Mass | 181.05000 |
| PSA | 110.43000 |
| LogP | 0.38890 |
| Index of Refraction | 1.5 |
| Hazard Codes | Xn |
|---|---|
| HS Code | 2931900090 |
| Precursor 0 | |
|---|---|
| DownStream 1 | |
| HS Code | 2931900090 |
|---|---|
| Summary | 2931900090. other organo-inorganic compounds. VAT:17.0%. Tax rebate rate:13.0%. Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward). MFN tariff:6.5%. General tariff:30.0% |