71395-14-7
71395-14-7 structure
- Name: Tocainide hydrochloride
- Chemical Name: tocainide
- CAS Number: 71395-14-7
- Molecular Formula: C11H17ClN2O
- Molecular Weight: 192.25800
- Catalog: Signaling Pathways Membrane Transporter/Ion Channel Sodium Channel
- Create Date: 2019-01-01 08:28:02
- Modify Date: 2024-01-10 19:21:57
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Tocainide hydrochloride is a sodium channel blocker, it blocks the sodium channels in the pain-producing foci in the nerve membranes. Tocainide hydrochloride is a primary amine analog of lidocaine, can be used for the treatment of tinnitus[1][2].
| Name | tocainide |
|---|---|
| Synonyms |
(+-)-2-amino-N-(2,6-dimethylphenyl)propionamide hydrochloride
4-Amino-2-[4,6-diamino-3-[3-amino-6-(aminomethyl)-5-hydroxyoxan-2-yl]oxy-2-hydroxycyclohexyl]oxy-6-(hydroxymethyl)oxane-3,5-diol sulfate Tobramycin sulfate [usan] Tocainidhydrochlorid 6'-propionoxylidide hydrochloride TOBRAMYCIN SULPHATE |
| Description | Tocainide hydrochloride is a sodium channel blocker, it blocks the sodium channels in the pain-producing foci in the nerve membranes. Tocainide hydrochloride is a primary amine analog of lidocaine, can be used for the treatment of tinnitus[1][2]. |
|---|---|
| Related Catalog | |
| Target |
IC50: sodium channel[1] |
| In Vivo | Tocainide (100 mg/kg) effectively suppresses ventricular ectopic activity in unanesthetized dogs with coronary occlusion. Termination of tocainide infusion in both digitalis toxicity and coronary occlusion models results in prompt return of ventricular ectopic activity[1]. |
| References |
| Molecular Formula | C11H17ClN2O |
|---|---|
| Molecular Weight | 192.25800 |
| Exact Mass | 192.12600 |
| PSA | 55.12000 |
| LogP | 2.36240 |
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H302 |
| Precautionary Statements | P301 + P312 + P330 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xi |
| RIDADR | UN1230 - class 3 - PG 2 - Methanol, solution |