7226-77-9

7226-77-9 structure

Name: 5-Hydroxymethyl-2’-deoxycytidine
Chemical Name: 5-(Hydroxymethyl)-2’-deoxycytidine
CAS Number: 7226-77-9
Molecular Formula: C₁₀H₁₅N₃O₅
Molecular Weight: 257.24
Catalog: Signaling Pathways Others Others
Create Date: 2018-08-27 05:01:50
Modify Date: 2026-07-21 16:28:33
5-Hydroxymethyl-2’-deoxycytidine (5hmdC) is an oxidation derivative of 5-methyl-2'-deoxycytidine (5-mdC) in DNA. 5-Hydroxymethyl-2’-deoxycytidine may serve as a marker of irreversibly damaged cells[1][2].

Name	5-(Hydroxymethyl)-2’-deoxycytidine
Synonyms	5-hydroxymethyl-2,4-dimethyl-pyrrole-3-carboxylic acid ethyl ester 5-(Hydroxymethyl)-2'-deoxycytidine 5-Hydroxymethyl-2,4-dimethyl-pyrrol-3-carbonsaeure-aethylester 5-Hydroxymethyl-2,4-dimethyl-3-pyrrolcarbonsaeure-ethylester

Description	5-Hydroxymethyl-2’-deoxycytidine (5hmdC) is an oxidation derivative of 5-methyl-2'-deoxycytidine (5-mdC) in DNA. 5-Hydroxymethyl-2’-deoxycytidine may serve as a marker of irreversibly damaged cells[1][2].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
References	[1]. Ewelina Zarakowska, et al. Oxidation Products of 5-Methylcytosine are Decreased in Senescent Cells and Tissues of Progeroid Mice. J Gerontol A Biol Sci Med Sci. 2018 Jul 9;73(8):1003-1009. [2]. Shuo Liu, et al. Quantitative assessment of Tet-induced oxidation products of 5-methylcytosine in cellular and tissue DNA. Nucleic Acids Res. 2013 Jul;41(13):6421-9.