56271-94-4

56271-94-4 structure

Name: Descarbamoyl Cefuroxime
Chemical Name: 7-{[2-Furyl(methoxyimino)acetyl]amino}-3-(hydroxymethyl)-8-oxo-5- thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
CAS Number: 56271-94-4
Molecular Formula: C₁₅H₁₅N₃O₇S
Molecular Weight: 381.36100
Catalog: Research Areas Infection
Create Date: 2018-12-24 17:46:57
Modify Date: 2024-01-02 09:42:50
Descarbamoyl cefuroxime is a degradation product of Cefuroxime. Descarbamoyl cefuroxime is also an intermediate for the synthesis of Cephalosporin antibiotics[1][2].

Name	7-{[2-Furyl(methoxyimino)acetyl]amino}-3-(hydroxymethyl)-8-oxo-5- thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Synonyms	7-PHENYLACETAMIDE-3-CHLOROMETHYL-CEPHALOSPORANIC ACID P-METHOXYBENZYL ESTER Descarbamoyl Cefuroxime GCLE:INTERMEDIATE FOR CEPHALOSPORIN 3-chloromethyl-7-phenylacetylaminocephalosporanic acid p-methoxybenzyl ester 7-PHENYLACETAMIDO-3-CHLOROMETHYLCEPHEM-4-CARBONICACID-PARA-METHOXYBENZYLESTER 7-phenylacetamido-3-chloromethylcephem-4-carbonicacidp-methoxybenzylester 7-PHENYLACETAMINO-3-CHLOROMETHYL-3-CEPHEM4-CARBOXYLIC ACID P-METHOXYBENZYL ESTER Cefuroxime Impurity 4

Description	Descarbamoyl cefuroxime is a degradation product of Cefuroxime. Descarbamoyl cefuroxime is also an intermediate for the synthesis of Cephalosporin antibiotics[1][2].
Related Catalog	Research Areas >> Infection
References	[1]. Vercheval C, et al. Stability of 90 mg/mL cefuroxime sodium solution for administration by continuous infusion. J Chemother. 2018 Oct - Dec;30(6-8):371-374. [2]. Takaya T, et al. Studies on beta-lactam antibiotics. III. Synthesis and enzymatic stability of 3-acyloxymethyl-7 beta-[(Z)-2-(2-amino-4-thiazolyl)-2-(methoxyimino)acetamido]-3-cephem-4-carboxylic acids. J Antibiot (Tokyo). 1981 Oct;34(10):1300-10.