1005036-73-6

1005036-73-6 structure

Name: (Rac)-Golgicide A
Chemical Name: Golgicide A
CAS Number: 1005036-73-6
Molecular Formula: C₁₇H₁₄F₂N₂
Molecular Weight: 284.30
Catalog: Research Areas Infection
Create Date: 2017-01-09 23:32:17
Modify Date: 2024-01-14 18:36:53
(Rac)-Golgicide A ((Rac)-GCA) is a racemate of Golgicide A. Golgicide A (GCA) is a potent, highly specific, and reversible inhibitor of the cis-Golgi ADP-ribosylation factor guanine nucleotide exchange factors (ArfGEF) GBF1[1].Golgicide A drastically reduced replication of coxsackievirus B3 (CVB3) and other human enterovirus species[2].

Name	Golgicide A
Synonyms	6,8-Difluoro-4-(3-pyridinyl)-3a,4,5,9b-tetrahydro-3H-cyclopenta[c ]quinoline

Description	(Rac)-Golgicide A ((Rac)-GCA) is a racemate of Golgicide A. Golgicide A (GCA) is a potent, highly specific, and reversible inhibitor of the cis-Golgi ADP-ribosylation factor guanine nucleotide exchange factors (ArfGEF) GBF1[1].Golgicide A drastically reduced replication of coxsackievirus B3 (CVB3) and other human enterovirus species[2].
Related Catalog	Research Areas >> Infection
References	[1]. Sáenz JB, et al. Golgicide A reveals essential roles for GBF1 in Golgi assembly and function. Nat Chem Biol. 2009 Mar;5(3):157-65. [2]. van der Linden L, et al. Differential effects of the putative GBF1 inhibitors Golgicide A and AG1478 on enterovirus replication. J Virol. 2010 Aug;84(15):7535-42.

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H319
Precautionary Statements	P305 + P351 + P338
Hazard Codes	Xi
RIDADR	NONH for all modes of transport