(Rac)-Golgicide A

Modify Date: 2024-01-14 18:36:53

(Rac)-Golgicide A Structure
(Rac)-Golgicide A structure
Common Name (Rac)-Golgicide A
CAS Number 1005036-73-6 Molecular Weight 284.30
Density N/A Boiling Point N/A
Molecular Formula C17H14F2N2 Melting Point N/A
MSDS Chinese USA Flash Point N/A
Symbol GHS07
GHS07
Signal Word Warning

 Use of (Rac)-Golgicide A


(Rac)-Golgicide A ((Rac)-GCA) is a racemate of Golgicide A. Golgicide A (GCA) is a potent, highly specific, and reversible inhibitor of the cis-Golgi ADP-ribosylation factor guanine nucleotide exchange factors (ArfGEF) GBF1[1].Golgicide A drastically reduced replication of coxsackievirus B3 (CVB3) and other human enterovirus species[2].

 Names

Name Golgicide A
Synonym More Synonyms

 (Rac)-Golgicide A Biological Activity

Description (Rac)-Golgicide A ((Rac)-GCA) is a racemate of Golgicide A. Golgicide A (GCA) is a potent, highly specific, and reversible inhibitor of the cis-Golgi ADP-ribosylation factor guanine nucleotide exchange factors (ArfGEF) GBF1[1].Golgicide A drastically reduced replication of coxsackievirus B3 (CVB3) and other human enterovirus species[2].
Related Catalog
References

[1]. Sáenz JB, et al. Golgicide A reveals essential roles for GBF1 in Golgi assembly and function. Nat Chem Biol. 2009 Mar;5(3):157-65.

[2]. van der Linden L, et al. Differential effects of the putative GBF1 inhibitors Golgicide A and AG1478 on enterovirus replication. J Virol. 2010 Aug;84(15):7535-42.

 Chemical & Physical Properties

Molecular Formula C17H14F2N2
Molecular Weight 284.30
Exact Mass 284.11300
PSA 24.92000
LogP 4.32430

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H319
Precautionary Statements P305 + P351 + P338
Hazard Codes Xi
RIDADR NONH for all modes of transport

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 Synonyms

6,8-Difluoro-4-(3-pyridinyl)-3a,4,5,9b-tetrahydro-3H-cyclopenta[c ]quinoline
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