478082-99-4
478082-99-4 structure
- Name: Ro4368554
- Chemical Name: 3-(benzenesulfonyl)-7-(4-methylpiperazin-1-yl)-1H-indole
- CAS Number: 478082-99-4
- Molecular Formula: C19H21N3O2S
- Molecular Weight: 355.45400
- Create Date: 2017-04-28 00:08:20
- Modify Date: 2024-04-09 12:02:37
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Ro4368554 is a 5-HT6 receptor antagonist. RO4368554 acts selectively at 5-HT6 receptors where it binds with a greater than 100-fold selectivity over other monoamine receptor subtypes (-log M pKi = 9.4 at 5-HT6 and 7.1 at 5-HT2A).
| Name | 3-(benzenesulfonyl)-7-(4-methylpiperazin-1-yl)-1H-indole |
|---|---|
| Synonyms |
7-(4-methyl-1-piperazinyl)-3-(phenylsulfonyl)-1H-Indole
3-benzenesulfonyl-7-(4-methyl-piperazin-1-yl)-1H-indole 3-phenylsulfonyl-7-(4-methyl-piperazin-1-yl)-1H-indole 1H-Indole,7-(4-methyl-1-piperazinyl)-3-(phenylsulfonyl) |
| Molecular Formula | C19H21N3O2S |
|---|---|
| Molecular Weight | 355.45400 |
| Exact Mass | 355.13500 |
| PSA | 64.79000 |
| LogP | 3.83620 |
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H302 |
| Hazard Codes | Xn |
| RIDADR | NONH for all modes of transport |