70351-51-8

70351-51-8 structure
70351-51-8 structure
  • Name: Supercinnamaldehyde
  • Chemical Name: (3Z)-1-Methyl-3-(2-oxopropylidene)-1,3-dihydro-2H-indol-2-one
  • CAS Number: 70351-51-8
  • Molecular Formula: C12H11NO2
  • Molecular Weight: 201.22
  • Catalog: Signaling Pathways Membrane Transporter/Ion Channel TRP Channel
  • Create Date: 2017-10-21 21:10:33
  • Modify Date: 2024-01-09 17:24:16
  • Supercinnamaldehyde is a potent transient receptor potential ankyrin 1 (TRPA1) activator with an EC50 value of 0.8 μM. Supercinnamaldehyde activates TRPA1 ion channels through covalent modification of cysteines[1].

Name (3Z)-1-Methyl-3-(2-oxopropylidene)-1,3-dihydro-2H-indol-2-one
Synonyms Bicyclo[3.1.1]heptan-2-one,3-[3-(trimethylsilyl)-2-butenyl]
(3E)-1-methyl-3-(2-oxopropyridene)-1,3-dihydro-2H-indol-2-one
3-((E)-3-trimethylsilyl-2-butenyl)bicyclo[3.3.1]-heptan-2-one
Description Supercinnamaldehyde is a potent transient receptor potential ankyrin 1 (TRPA1) activator with an EC50 value of 0.8 μM. Supercinnamaldehyde activates TRPA1 ion channels through covalent modification of cysteines[1].
Related Catalog
References

[1]. Macpherson LJ, et, al. Noxious compounds activate TRPA1 ion channels through covalent modification of cysteines. Nature. 2007 Feb 1;445(7127):541-5.

Molecular Formula C12H11NO2
Molecular Weight 201.22
Exact Mass 201.07900
PSA 37.38000
LogP 1.70040
Storage condition 2-8°C
Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi
Risk Phrases 36/37/38-52/53
Safety Phrases 26-36/37-61
RIDADR NONH for all modes of transport