7370-21-0
7370-21-0 structure
- Name: SIB-1893
- Chemical Name: 2-Methyl-6-[(E)-2-phenylvinyl]pyridine
- CAS Number: 7370-21-0
- Molecular Formula: C14H13N
- Molecular Weight: 195.26000
- Create Date: 2016-08-26 21:09:14
- Modify Date: 2025-08-26 17:13:56
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SIB-1893 is a highly selective non-competitive antagonist for the metabotropic glutamate mGlu5 receptor subtype; displays an IC50 value of 0.3 μM at hmGlu5, compared with > 100 μM at hmGlu1b, hmGlu2, hmGlu6, hmGlu7 and hmGlu8. It positive allosteric modulator at mGlu4 receptors.
| Name | 2-Methyl-6-[(E)-2-phenylvinyl]pyridine |
|---|---|
| Synonyms |
6-METHYL-2-(NAPHTHALEN-2-YL)BENZOIC ACID
2-Methyl-6-(2-naphthyl)-benzoesaeure (E)-2-methyl-6-styrylpyridine 2-Methyl-6-(2-phenylethenyl)pyridine (E)-2-methyl-6-styrypyridine (E)-6-methyl-2-styryl-pyridine 2-methyl-6-[(E)-2-phenylethenyl]pyridine |
| Molecular Formula | C14H13N |
|---|---|
| Molecular Weight | 195.26000 |
| Exact Mass | 195.10500 |
| PSA | 12.89000 |
| LogP | 3.56040 |
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H315-H319-H335 |
| Precautionary Statements | P261-P305 + P351 + P338 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| RIDADR | NONH for all modes of transport |