474943-05-0

474943-05-0 structure

Name: C12-NBD Sphinganine
Chemical Name: N-[(2S,3R)-1,3-Dihydroxy-2-octadecanyl]-12-[(7-nitro-2,1,3-benzox adiazol-4-yl)amino]dodecanamide
CAS Number: 474943-05-0
Molecular Formula: C₃₆H₆₃N₅O₆
Molecular Weight: 661.915
Catalog: Research Areas Others
Create Date: 2016-07-28 07:43:15
Modify Date: 2023-10-16 10:44:58
C12-NBD Sphinganine is a fluorescent ceramidase substrate. C12-NBD Sphinganine can be used for the measurement of alkaline and neutral ceramidase activity from a variety of sources[1][2][3].

Name	N-[(2S,3R)-1,3-Dihydroxy-2-octadecanyl]-12-[(7-nitro-2,1,3-benzox adiazol-4-yl)amino]dodecanamide
Synonyms	N-[(2S,3R)-1,3-Dihydroxy-2-octadecanyl]-12-[(7-nitro-2,1,3-benzoxadiazol-4-yl)amino]dodecanamide Dodecanamide, N-[(1S,2R)-2-hydroxy-1-(hydroxymethyl)heptadecyl]-12-[(7-nitro-2,1,3-benzoxadiazol-4-yl)amino]-

Description	C12-NBD Sphinganine is a fluorescent ceramidase substrate. C12-NBD Sphinganine can be used for the measurement of alkaline and neutral ceramidase activity from a variety of sources[1][2][3].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
References	[1]. Rigogliuso S, et al. An active form of sphingosine kinase-1 is released in the extracellular medium as component of membrane vesicles shed by two human tumor cell lines. J Oncol. 2010;2010:509329. [2]. Okino N, et al. Expression, purification, and characterization of a recombinant neutral ceramidase from Mycobacterium tuberculosis. Biosci Biotechnol Biochem. 2010;74(2):316-21. [3]. Vijai Kumar Reddy T, et al. Design, synthesis and in vitro biological evaluation of short-chain C12-sphinganine and its 1,2,3-triazole analogs as potential antimicrobial and anti-biofilm agents. Eur J Med Chem. 2016 Aug 8;118:98-106.

Hazard Codes	T+