C12-NBD Sphinganine

Modify Date: 2024-09-10 19:59:13

C12-NBD Sphinganine structure	Common Name	C12-NBD Sphinganine
	CAS Number	474943-05-0	Molecular Weight	661.915
	Density	1.1±0.1 g/cm3	Boiling Point	N/A
	Molecular Formula	C₃₆H₆₃N₅O₆	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of C12-NBD Sphinganine

C12-NBD Sphinganine is a fluorescent ceramidase substrate. C12-NBD Sphinganine can be used for the measurement of alkaline and neutral ceramidase activity from a variety of sources[1][2][3].

Name	N-[(2S,3R)-1,3-Dihydroxy-2-octadecanyl]-12-[(7-nitro-2,1,3-benzox adiazol-4-yl)amino]dodecanamide
Synonym	More Synonyms

Description	C12-NBD Sphinganine is a fluorescent ceramidase substrate. C12-NBD Sphinganine can be used for the measurement of alkaline and neutral ceramidase activity from a variety of sources[1][2][3].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
References	[1]. Rigogliuso S, et al. An active form of sphingosine kinase-1 is released in the extracellular medium as component of membrane vesicles shed by two human tumor cell lines. J Oncol. 2010;2010:509329. [2]. Okino N, et al. Expression, purification, and characterization of a recombinant neutral ceramidase from Mycobacterium tuberculosis. Biosci Biotechnol Biochem. 2010;74(2):316-21. [3]. Vijai Kumar Reddy T, et al. Design, synthesis and in vitro biological evaluation of short-chain C12-sphinganine and its 1,2,3-triazole analogs as potential antimicrobial and anti-biofilm agents. Eur J Med Chem. 2016 Aug 8;118:98-106.

Description

C12-NBD Sphinganine is a fluorescent ceramidase substrate. C12-NBD Sphinganine can be used for the measurement of alkaline and neutral ceramidase activity from a variety of sources[1][2][3].

Related Catalog

Research Areas >> Others

Signaling Pathways >> Others >> Others

References

[1]. Rigogliuso S, et al. An active form of sphingosine kinase-1 is released in the extracellular medium as component of membrane vesicles shed by two human tumor cell lines. J Oncol. 2010;2010:509329.

[2]. Okino N, et al. Expression, purification, and characterization of a recombinant neutral ceramidase from Mycobacterium tuberculosis. Biosci Biotechnol Biochem. 2010;74(2):316-21.

[3]. Vijai Kumar Reddy T, et al. Design, synthesis and in vitro biological evaluation of short-chain C12-sphinganine and its 1,2,3-triazole analogs as potential antimicrobial and anti-biofilm agents. Eur J Med Chem. 2016 Aug 8;118:98-106.

Density	1.1±0.1 g/cm3
Molecular Formula	C₃₆H₆₃N₅O₆
Molecular Weight	661.915
Exact Mass	661.477844
PSA	169.82000
LogP	11.57
Index of Refraction	1.540

Hazard Codes	T+

N-[(2S,3R)-1,3-Dihydroxy-2-octadecanyl]-12-[(7-nitro-2,1,3-benzoxadiazol-4-yl)amino]dodecanamide

Dodecanamide, N-[(1S,2R)-2-hydroxy-1-(hydroxymethyl)heptadecyl]-12-[(7-nitro-2,1,3-benzoxadiazol-4-yl)amino]-

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C12-NBD Sphinganine

Use of C12-NBD Sphinganine

Names

C12-NBD Sphinganine Biological Activity

Chemical & Physical Properties

Safety Information

Synonyms

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.