26309-95-5
26309-95-5 structure
- Name: Pivampicillin Hydrochloride
- Chemical Name: 2,2-dimethylpropanoyloxymethyl (2S,5R,6R)-6-[[(2R)-2-amino-2-phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate,hydrochloride
- CAS Number: 26309-95-5
- Molecular Formula: C22H30ClN3O6S
- Molecular Weight: 500.00800
- Create Date: 2016-09-23 11:51:58
- Modify Date: 2024-04-08 22:18:39
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Pivampicillin Hydrochloride is the hydrochloride salt form of an orally active pivalate ester of ampicillin with antibacterial activity. Pivampicillin is hydrolyzed into its active form ampicillin by esterases. Ampicillin binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This interrupts bacterial cell wall synthesis and results in the weakening of the bacterial cell wall, eventually causing cell lysis.
| Name | 2,2-dimethylpropanoyloxymethyl (2S,5R,6R)-6-[[(2R)-2-amino-2-phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate,hydrochloride |
|---|---|
| Synonyms |
Pivatil
Alphacillin Alphacilina Devonium Centurina Diancina Sanguicillin Berocillin pivampicillin,hydrochloride Inacilin Maxifen ((R)-amino-phenyl-methyl)-penicillin 2,2-dimethyl-propionyloxymethyl ester,hydrochloride pivampicillin HCl |
| Molecular Formula | C22H30ClN3O6S |
|---|---|
| Molecular Weight | 500.00800 |
| Exact Mass | 499.15400 |
| PSA | 156.82000 |
| LogP | 3.60400 |