Pivampicillin Hydrochloride

Modify Date: 2024-04-08 22:18:39

Pivampicillin Hydrochloride Structure
Pivampicillin Hydrochloride structure
Common Name Pivampicillin Hydrochloride
CAS Number 26309-95-5 Molecular Weight 500.00800
Density N/A Boiling Point N/A
Molecular Formula C22H30ClN3O6S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Pivampicillin Hydrochloride


Pivampicillin Hydrochloride is the hydrochloride salt form of an orally active pivalate ester of ampicillin with antibacterial activity. Pivampicillin is hydrolyzed into its active form ampicillin by esterases. Ampicillin binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This interrupts bacterial cell wall synthesis and results in the weakening of the bacterial cell wall, eventually causing cell lysis.

 Names

Name 2,2-dimethylpropanoyloxymethyl (2S,5R,6R)-6-[[(2R)-2-amino-2-phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate,hydrochloride
Synonym More Synonyms

 Chemical & Physical Properties

Molecular Formula C22H30ClN3O6S
Molecular Weight 500.00800
Exact Mass 499.15400
PSA 156.82000
LogP 3.60400

 Synonyms

Pivatil
Alphacillin
Alphacilina
Devonium
Centurina
Diancina
Sanguicillin
Berocillin
pivampicillin,hydrochloride
Inacilin
Maxifen
((R)-amino-phenyl-methyl)-penicillin 2,2-dimethyl-propionyloxymethyl ester,hydrochloride
pivampicillin HCl