1391052-76-8
1391052-76-8 structure
- Name: 3-O-Decyclopropyl Roflumilast
- Chemical Name: 3-O-Decyclopropyl Roflumilast
- CAS Number: 1391052-76-8
- Molecular Formula: C13H8Cl2F2N2O3
- Molecular Weight: 349.117
- Catalog: Signaling Pathways Metabolic Enzyme/Protease Phosphodiesterase (PDE)
- Create Date: 2018-04-08 08:00:00
- Modify Date: 2025-08-21 12:38:24
-
Roflumilast Impurity E is the impurity of Roflumilast. Roflumilast(Daliresp) is a drug which acts as a selective and long-acting inhibitor of the enzyme PDE-4 with an IC50 value of 0.8 nM.
| Name | 3-O-Decyclopropyl Roflumilast |
|---|---|
| Synonyms |
Benzamide, N-(3,5-dichloro-4-pyridinyl)-4-(difluoromethoxy)-3-hydroxy-
N-(3,5-Dichloro-4-pyridinyl)-4-(difluoromethoxy)-3-hydroxybenzamide N-(3,5-dichloropyridin-4-yl)-4-(difluoroMethoxy)-3-hydroxybenzaMide 3-(hydroxy)-N-(3,5-dichloro-4-pyridinyl) -4-difluoromethoxy) benzamide Roflumilast Impurity E Roflumilast Impurity 2 |
| Description | Roflumilast Impurity E is the impurity of Roflumilast. Roflumilast(Daliresp) is a drug which acts as a selective and long-acting inhibitor of the enzyme PDE-4 with an IC50 value of 0.8 nM. |
|---|---|
| Related Catalog |
| Density | 1.6±0.1 g/cm3 |
|---|---|
| Boiling Point | 397.4±42.0 °C at 760 mmHg |
| Molecular Formula | C13H8Cl2F2N2O3 |
| Molecular Weight | 349.117 |
| Flash Point | 194.2±27.9 °C |
| Exact Mass | 347.988007 |
| PSA | 71.45000 |
| LogP | 3.37 |
| Vapour Pressure | 0.0±1.0 mmHg at 25°C |
| Index of Refraction | 1.626 |
| Storage condition | 2-8℃ |