Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: fusidic acid
Price: ￥708.0/1g
Purity: 98.0%
Stocking Period: 2 Day
Contact: Liu jia

DC Chemicals Limited
China
Product Name: Anhydrous Fusidic Acid
Price: ￥Inquiry/1g
Purity: 98.9%
Stocking Period: 1 Day
Contact: Tony Cao

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Fusidine
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

Henan Tianfu Chemical Co., Ltd.
China
Product Name: fusidic acid
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Stocking Period: Inquiry
Contact: Anson

6990-06-3

6990-06-3 structure

6990-06-3 structure

Name: fusidic acid
Chemical Name: fusidic acid
CAS Number: 6990-06-3
Molecular Formula: C₃₁H₄₈O₆
Molecular Weight: 516.709
Catalog: API Antibiotics Other antibiotics
Create Date: 2018-04-11 08:00:00
Modify Date: 2024-01-01 23:00:00
Fusidic acid (Fusidate) is a bacteriostatic antibiotic[1][2][3].

Name	fusidic acid
Synonyms	(2Z)-2-[(3α,4α,5α,8α,9β,11α,13α,14β,16β,17Z)-16-(acetyloxy)-3,11-dihydroxy-4,8,10,14-tetramethylgonan-17-ylidene]-6-methylhept-5-enoic acid Fucidic acid Fusidate sodium EINECS 230-256-0 fusidic acid Fusidin FUCIDIN (2Z)-2-[(3R,4S,5S,8S,9S,10S,11R,13R,14S,16S)-16-acetyloxy-3,11-dihydroxy-4,8,10,14-tetramethyl-2,3,4,5,6,7,9,11,12,13,15,16-dodecahydro-1H-cyclopenta[a]phenanthren-17-ylidene]-6-methylhept-5-enoic acid (2Z)-2-[(3α,4α,5α,8α,9β,11α,13α,14β,16β,17Z)-16-Acetoxy-3,11-dihydroxy-4,8,10,14-tetramethylgonan-17-ylidene]-6-methylhept-5-enoic acid Fusidate 5-Heptenoic acid, 2-[(3α,4α,5α,8α,9β,11α,13α,14β,16β,17Z)-16-(acetyloxy)-3,11-dihydroxy-4,8,10,14-tetramethylgonan-17-ylidene]-6-methyl-, (2Z)- Ramycin fusdic acid (3α,4α,5α,8α,9β,11α,13α,14β,16β,17Z)-16-Acetoxy-3,11-dihydroxy-4,8,14-trimethyl-18-norcholesta-17,24-dien-21-oic acid Fucithalmic Fucidin acid MFCD00865135 3,11,16-Trihydroxy-4,8,10,14-tetramethyl-17-(1'-carboxyisohept-4'-enylidene)cyclopentanoperhydrophenanthrene 16-Acetate FusidicAcid 29-Nordammara-17(20),24-dien-21-oic acid, 16-(acetyloxy)-3,11-dihydroxy-, (3α,4α,8α,9β,11α,13α,14β,16β,17Z)- (3a,4a,8a,9b,11a,13a,14b,16b,17Z)-16-(Acetyloxy)-3,11-dihydroxy-29-nordammara-17(20),24-dien-21-oic Acid Diethanolamine fusidate Fusidine

Description	Fusidic acid (Fusidate) is a bacteriostatic antibiotic[1][2][3].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Bacterial
Target	Bacterial[1][2][3]
References	[1]. Falagas ME, et al. Potential of old-generation antibiotics to address current need for new antibiotics. Expert Rev Anti Infect Ther. 2008 Oct;6(5):593-600. [2]. Leclercq R, et al. In vitro activity of fusidic acid against streptococci isolated from skin and soft tissue infections. J Antimicrob Chemother. 2000 Jan;45(1):27-9. [3]. Spelman D, et al. Fusidic acid in skin and soft tissue infections. Int J Antimicrob Agents. 1999 Aug;12 Suppl 2:S59-66.

Density	1.2±0.1 g/cm3
Boiling Point	635.6±55.0 °C at 760 mmHg
Melting Point	190-192ºC
Molecular Formula	C₃₁H₄₈O₆
Molecular Weight	516.709
Flash Point	197.7±25.0 °C
Exact Mass	516.345093
PSA	104.06000
LogP	6.41
Vapour Pressure	0.0±4.2 mmHg at 25°C
Index of Refraction	1.558
Storage condition	2-8°C

CHEMICAL IDENTIFICATION

RTECS NUMBER :: RC1350000

CHEMICAL NAME :: 29-Nordammara-17(20),24-dien-21-oic acid, 16-(acetyloxy)-3,11-dihydroxy-, (3-alpha,4-alpha, 8-alpha,9-beta,11-alpha,13-alpha,14-beta,16-beta,17Z) -

CAS REGISTRY NUMBER :: 6990-06-3

LAST UPDATED :: 199603

DATA ITEMS CITED :: 7

MOLECULAR FORMULA :: C31-H48-O6

MOLECULAR WEIGHT :: 516.79

WISWESSER LINE NOTATION :: L E5 B666 FYTJ A CQ FUYVQ3UY GOV1 I J N OQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Human - woman

DOSE/DURATION :: 420 mg/kg/2W-I

TOXIC EFFECTS :: Blood - leukopenia Blood - thrombocytopenia

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 165 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1200 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 180 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Unreported

DOSE :: 15 gm/kg

SEX/DURATION :: female 9-14 day(s) after conception

TOXIC EFFECTS :: Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) Reproductive - Effects on Embryo or Fetus - fetal death

MUTATION DATA

TYPE OF TEST :: Cytogenetic analysis

TEST SYSTEM :: Insect - Drosophila melanogaster Cells - not otherwise specified

DOSE/DURATION :: 100 mg/L

REFERENCE :: CLDFAT Cell Differentiation. (Limerick, Ireland) V.1-24, 1972-88. Volume(issue)/page/year: 2,97,1973

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H302
Precautionary Statements	P301 + P312 + P330
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xn
Risk Phrases	R22
Safety Phrases	36
RIDADR	NONH for all modes of transport
RTECS	RC1350000
HS Code	2942000000

HS Code	2942000000