141282-35-1

141282-35-1 structure
141282-35-1 structure
  • Name: Amino-PEG5-CH2CO2H
  • Chemical Name: [2-(2-{2-[2-(2-amino-ethoxy)-ethoxy]-ethoxy}-ethoxy)-ethoxy]acetic acid
  • CAS Number: 141282-35-1
  • Molecular Formula: C12H25NO7
  • Molecular Weight: 295.32900
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2016-01-31 22:17:25
  • Modify Date: 2025-08-25 18:18:42
  • Amino-PEG5-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name [2-(2-{2-[2-(2-amino-ethoxy)-ethoxy]-ethoxy}-ethoxy)-ethoxy]acetic acid
Synonyms h2n-peg5-ch2cooh
Description Amino-PEG5-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

Molecular Formula C12H25NO7
Molecular Weight 295.32900
Exact Mass 295.16300
PSA 109.47000
Hazard Codes Xi
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