76939-46-3

76939-46-3 structure

Name: 8-Bromo-cAMP sodium salt
Chemical Name: 8-Bromo-cAMP, sodium salt,8-Bromoadenosine-3',5'-cyclicmonophosphatesodiumsalt
CAS Number: 76939-46-3
Molecular Formula: C₁₀H₁₀BrN₅NaO₆P
Molecular Weight: 430.08
Catalog: Biochemical Nucleoside drugs Nucleoside intermediate
Create Date: 2018-08-22 13:19:15
Modify Date: 2024-01-02 12:06:58
8-Bromo-cAMP sodium salt (8-Br-Camp sodium salt), a cyclic AMP analog, is an activator of cyclic AMP-dependent protein kinase (PKA)[1].

Name	8-Bromo-cAMP, sodium salt,8-Bromoadenosine-3',5'-cyclicmonophosphatesodiumsalt
Synonyms	4H-Furo[3,2-d]-1,3,2-dioxaphosphorin-7-ol, 6-(6-amino-8-bromo-9H-purin-9-yl)tetrahydro-2-hydroxy-, 2-oxide, sodium salt, (4aR,6R,7R,7aS)- (1:1) 8-BROMOADENOSINE 3':5'-CYCLICMONOPHOSPHA TE SODIUM CAMP,8-BR,NA 8-BROMOADENOSINE-3',5'-CYCLOPHOSPHATE SODIUM SALT 8-BR-CAMP NA Sodium (4aR,6R,7R,7aS)-6-(6-amino-8-bromo-9H-purin-9-yl)-7-hydroxytetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-2-olate 2-oxide 8-BROMO-CAMP,NA 8-bromoadenosine 3:5-cyclic*monophosphate sodiu 8-BROMO-CAMP,SODIUM SALT 8-BR-CAMP SODIUM SALT 8-Bromoadenosine 3',5'-phosphoric acid sodium salt MFCD00005844 8-BROM-ADENOSIN-3',5'-CYCLOPHOSPHAT

Description	8-Bromo-cAMP sodium salt (8-Br-Camp sodium salt), a cyclic AMP analog, is an activator of cyclic AMP-dependent protein kinase (PKA)[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Protein Tyrosine Kinase/RTK >> PKA Signaling Pathways >> Stem Cell/Wnt >> PKA
Target	PKA[1]
In Vitro	8-Bromo-cAMP sodium salt is a brominated derivative of cyclic AMP. 8-Bromo-cAMP sodium salt enhances the efficiency of cellular reprogramming. 8-Bromo-cAMP sodium salt improves the reprogramming efficiency of human neonatal foreskin fibroblast (HFF1) cells. 8-Bromo-cAMP sodium salt inhibits proliferation, induce differentiation and apoptosis in a malignant glioma cell line (A-172) and an esophageal cancer cell line (Eca-109)[1].
References	[1]. Wang Y, et al. A cyclic AMP analog, 8-Br-cAMP, enhances the induction of pluripotency in human fibroblast cells. Stem Cell Rev. 2011 Jun;7(2):331-41.

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