Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Leptophos
Price:
Purity: 98.0%
Stocking Period: 10 Day
Contact: Yang

DC Chemicals Limited
China
Product Name: Leptophos
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

21609-90-5

21609-90-5 structure

21609-90-5 structure

Name: Leptophos
Chemical Name: leptophos
CAS Number: 21609-90-5
Molecular Formula: C₁₃H₁₀BrCl₂O₂PS
Molecular Weight: 412.06600
Catalog: Chemical pesticide Insecticide Organochlorine insecticide
Create Date: 2018-06-24 15:58:10
Modify Date: 2024-01-27 20:42:39
Leptophos is an organophosphate insecticide.

Name	leptophos
Synonyms	LMB CI-940 (Ξ)-[O-(4-bromo-2,5-dichlorophenyl) O-methyl phenylphosphonothioate] O-(4-Bromo-2,5-dichlorophenyl) O-methyl phenylphosphonothioate nk711 MBCP O-(4-bromo-2,5-dichlorophenyl) O-methyl P-phenylphosphonothioate (RS)-(O-4-bromo-2,5-dichlorophenyl O-methyl phenylphosphonothioate) PSL Abar EINECS 244-472-8 lepton MFCD06795848 V.C.S. Fosvel LEPTOMYCIN B

Density	1.66 g/cm3
Boiling Point	444.4ºC at 760 mmHg
Melting Point	71-73 °C
Molecular Formula	C₁₃H₁₀BrCl₂O₂PS
Molecular Weight	412.06600
Flash Point	>100 °C
Exact Mass	409.87000
PSA	60.36000
LogP	6.06670
Vapour Pressure	1.12E-07mmHg at 25°C
Index of Refraction	1.651

CHEMICAL IDENTIFICATION

RTECS NUMBER :: TB1720000

CHEMICAL NAME :: Phosphonothioic acid, phenyl-, O-(4-bromo-2,5-dichlorophenyl) O-methyl ester

CAS REGISTRY NUMBER :: 21609-90-5

LAST UPDATED :: 199710

DATA ITEMS CITED :: 20

MOLECULAR FORMULA :: C13-H10-Br-Cl2-O2-P-S

MOLECULAR WEIGHT :: 412.07

WISWESSER LINE NOTATION :: GR DG BE EOPS&R&O1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 19 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 44 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 135 mg/kg

TOXIC EFFECTS :: Sense Organs and Special Senses (Eye) - lacrimation Gastrointestinal - hypermotility, diarrhea Blood - hemorrhage

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 65 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 120 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 124 mg/kg

TOXIC EFFECTS :: Sense Organs and Special Senses (Eye) - lacrimation Behavioral - ataxia Gastrointestinal - hypermotility, diarrhea

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 800 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Bird - chicken

DOSE/DURATION :: 4700 mg/kg

TOXIC EFFECTS :: Peripheral Nerve and Sensation - flaccid paralysis without anesthesia (usually neuromuscular blockage) Behavioral - changes in motor activity (specific assay) Behavioral - ataxia

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Mammal - species unspecified

DOSE/DURATION :: 50 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 14280 mg/kg/12W-C

TOXIC EFFECTS :: Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol) Nutritional and Gross Metabolic - weight loss or decreased weight gain Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - true cholinesterase

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Mammal - dog

DOSE/DURATION :: 1200 mg/kg/30D-I

TOXIC EFFECTS :: Peripheral Nerve and Sensation - spastic paralysis with or without sensory change Peripheral Nerve and Sensation - structural change in nerve or sheath Behavioral - ataxia

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Bird - chicken

DOSE/DURATION :: 1200 mg/kg/60D-I

TOXIC EFFECTS :: Spinal Cord - other degenerative changes Peripheral Nerve and Sensation - spastic paralysis with or without sensory change Behavioral - ataxia

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Bird - chicken

DOSE/DURATION :: 900 mg/kg/90D-I

TOXIC EFFECTS :: Spinal Cord - other degenerative changes Peripheral Nerve and Sensation - spastic paralysis with or without sensory change Behavioral - ataxia

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Bird - duck

DOSE/DURATION :: 520 mg/kg/20D-C

TOXIC EFFECTS :: Spinal Cord - other degenerative changes Behavioral - ataxia Nutritional and Gross Metabolic - weight loss or decreased weight gain

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Bird - duck

DOSE/DURATION :: 300 mg/kg/30D-I

TOXIC EFFECTS :: Peripheral Nerve and Sensation - spastic paralysis with or without sensory change Behavioral - ataxia

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Mammal - domestic

DOSE/DURATION :: 900 mg/kg/26W-I

TOXIC EFFECTS :: Brain and Coverings - other degenerative changes Spinal Cord - other degenerative changes Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - true cholinesterase

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 8125 ug/kg

SEX/DURATION :: female 8-20 day(s) after conception

TOXIC EFFECTS :: Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)

MUTATION DATA

TYPE OF TEST :: Sister chromatid exchange

TEST SYSTEM :: Rodent - hamster Ovary

DOSE/DURATION :: 300 umol/L

REFERENCE :: JTEHD6 Journal of Toxicology and Environmental Health. (Hemisphere Pub., 1025 Vermont Ave., NW, Washington, DC 20005) V.1- 1975/76- Volume(issue)/page/year: 8,939,1981 *** REVIEWS *** TOXICOLOGY REVIEW RREVAH Residue Reviews. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 07094) V.1- 1962- Volume(issue)/page/year: 63,1,1976

Symbol	GHS06, GHS08, GHS09
Signal Word	Danger
Hazard Statements	H301-H312-H370-H410
Precautionary Statements	P260-P273-P307 + P311-P501
Personal Protective Equipment	Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges
Hazard Codes	T: Toxic;N: Dangerous for the environment;
Risk Phrases	21-25-39/25-50/53
Safety Phrases	S25-S36/37/39-S45-S60-S61-S23
RIDADR	2783
RTECS	TB1720000
Packaging Group	II
Hazard Class	6.1(a)
HS Code	2930909090

1940-42-7 structure

1940-42-7

~%

21609-90-5 structure

21609-90-5

Literature: Synthesis, , # 9 p. 731 - 733

3497-00-5 structure

3497-00-5

~%

21609-90-5 structure

21609-90-5

Literature: Synthesis, , # 9 p. 731 - 733

67-56-1 structure

67-56-1

50654-88-1 structure

50654-88-1

~%

21609-90-5 structure

21609-90-5

Literature: Synthesis, , # 9 p. 731 - 733

Precursor 4
1940-42-7 3497-00-5 67-56-1 50654-88-1
DownStream 1
6840-11-5

HS Code	2930909090
Summary	2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%