41552-82-3
41552-82-3 structure
- Name: N6-Cyclopentyladenosine
- Chemical Name: (2R,3R,4S,5R)-2-(6-(Cyclopentylamino)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol
- CAS Number: 41552-82-3
- Molecular Formula: C15H21N5O4
- Molecular Weight: 335.36
- Catalog: Signaling Pathways GPCR/G Protein Adenosine Receptor
- Create Date: 2018-06-22 21:22:07
- Modify Date: 2024-01-02 11:28:59
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N6-Cyclopentyladenosine (CPA) is a selective Adenosine A1 receptor agonist, with Ki values of 2.3 nM, 790 nM and 43 nM for human A1, A2A and A3 receptors, respectively[1][2].
| Name | (2R,3R,4S,5R)-2-(6-(Cyclopentylamino)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol |
|---|---|
| Synonyms | N6-Cyclopentyladenosine |
| Description | N6-Cyclopentyladenosine (CPA) is a selective Adenosine A1 receptor agonist, with Ki values of 2.3 nM, 790 nM and 43 nM for human A1, A2A and A3 receptors, respectively[1][2]. |
|---|---|
| Related Catalog | |
| Target |
Ki: 2.3 nM (A1), 790 nM (A2A), 43 nM(A3)[1]. |
| References |
| Density | 1.78g/cm3 |
|---|---|
| Boiling Point | 673.4ºC at 760 mmHg |
| Molecular Formula | C15H21N5O4 |
| Molecular Weight | 335.36 |
| Flash Point | 361.1ºC |
| Exact Mass | 335.15900 |
| PSA | 125.55000 |
| Index of Refraction | 1.816 |
| Storage condition | 2-8℃ |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| RIDADR | NONH for all modes of transport |
|
~79%
41552-82-3 |
| Literature: Ottria, Roberta; Casati, Silvana; Baldoli, Erika; Maier, Jeanette A.M.; Ciuffreda, Pierangela Bioorganic and Medicinal Chemistry, 2010 , vol. 18, # 23 p. 8396 - 8402 |
|
~70%
41552-82-3 |
| Literature: Vittori, Sauro; Lorenzen, Anna; Stannek, Christina; Costanzi, Stefano; Volpini, Rosaria; Ijzerman, Adriaan P.; Von Frijtag Drabbe Kunzel, Jakobien K.; Cristalli, Gloria Journal of Medicinal Chemistry, 2000 , vol. 43, # 2 p. 250 - 260 |
|
~85%
41552-82-3 |
| Literature: Fletcher, Steven Tetrahedron Letters, 2010 , vol. 51, # 22 p. 2948 - 2950 |
|
~%
41552-82-3 |
| Literature: Vittori, Sauro; Lorenzen, Anna; Stannek, Christina; Costanzi, Stefano; Volpini, Rosaria; Ijzerman, Adriaan P.; Von Frijtag Drabbe Kunzel, Jakobien K.; Cristalli, Gloria Journal of Medicinal Chemistry, 2000 , vol. 43, # 2 p. 250 - 260 |
|
~%
41552-82-3 |
| Literature: Vittori, Sauro; Lorenzen, Anna; Stannek, Christina; Costanzi, Stefano; Volpini, Rosaria; Ijzerman, Adriaan P.; Von Frijtag Drabbe Kunzel, Jakobien K.; Cristalli, Gloria Journal of Medicinal Chemistry, 2000 , vol. 43, # 2 p. 250 - 260 |
|
~%
41552-82-3 |
| Literature: Inotek Pharmaceuticals Corporation Patent: US2007/238694 A1, 2007 ; Location in patent: Page/Page column 130 ; |
| Precursor 5 | |
|---|---|
| DownStream 0 | |