179985-52-5
179985-52-5 structure
- Name: A812511
- Chemical Name: N-(4-cyano-3-methylisoquinolin-1-yl)acetamide
- CAS Number: 179985-52-5
- Molecular Formula: C13H11N3O
- Molecular Weight: 225.25
- Catalog: Signaling Pathways Protein Tyrosine Kinase/RTK PKA
- Create Date: 2019-01-25 15:54:53
- Modify Date: 2025-08-27 19:52:30
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PKA-IN-1 is a potent and selective cyclic AMP-dependent protein kinase (PKA) catalytic subunit (cAK) inhibitor with an IC50 of 0.03 μM[1].
| Name | N-(4-cyano-3-methylisoquinolin-1-yl)acetamide |
|---|---|
| Synonyms |
1-ACETAMIDO-4-CYANO-3-METHYLISOQUINOLINE
1-Acetamido-3-methyl-4-cyanosoquinoline |
| Description | PKA-IN-1 is a potent and selective cyclic AMP-dependent protein kinase (PKA) catalytic subunit (cAK) inhibitor with an IC50 of 0.03 μM[1]. |
|---|---|
| Related Catalog | |
| Target |
IC50: 0.03 μM (cAK)[1] |
| References |
| Density | 1.24g/cm3 |
|---|---|
| Boiling Point | 489.7ºC at 760 mmHg |
| Melting Point | 200-202ºC |
| Molecular Formula | C13H11N3O |
| Molecular Weight | 225.25 |
| Flash Point | 250ºC |
| Exact Mass | 225.09000 |
| PSA | 65.78000 |
| LogP | 2.44628 |
| Vapour Pressure | 9.74E-10mmHg at 25°C |
| Index of Refraction | 1.632 |