179985-52-5

179985-52-5 structure

Name: A812511
Chemical Name: N-(4-cyano-3-methylisoquinolin-1-yl)acetamide
CAS Number: 179985-52-5
Molecular Formula: C₁₃H₁₁N₃O
Molecular Weight: 225.25
Catalog: Signaling Pathways Protein Tyrosine Kinase/RTK PKA
Create Date: 2019-01-25 15:54:53
Modify Date: 2026-08-14 17:33:58
PKA-IN-1 is a potent and selective cyclic AMP-dependent protein kinase (PKA) catalytic subunit (cAK) inhibitor with an IC50 of 0.03 μM[1].

Name	N-(4-cyano-3-methylisoquinolin-1-yl)acetamide
Synonyms	N-(4-Cyano-3-methylisoquinolin-1-yl)acetamide 1-Acetamido-3-methyl-4-cyanosoquinoline 1-ACETAMIDO-3-METHYL-4-CYANOSOQUINOLINE Acetamide,N-(4-cyano-3-methyl-1-isoquinolinyl) 1-ACETAMIDO-4-CYANO-3-METHYLISOQUINOLINE 1-ACETAMIDO-3-METHYL-4-CYANOISOQUINOLINE PKA-IN-1, 10 mM in DMSO N-(4-Cyano-3-Methyl-1-isoquinolinyl)acetaMide 1-Acetamido-3-methyl-4-cyanosoqinoline

Description	PKA-IN-1 is a potent and selective cyclic AMP-dependent protein kinase (PKA) catalytic subunit (cAK) inhibitor with an IC50 of 0.03 μM[1].
Related Catalog	Signaling Pathways >> Protein Tyrosine Kinase/RTK >> PKA Signaling Pathways >> Stem Cell/Wnt >> PKA Research Areas >> Inflammation/Immunology
Target	IC50: 0.03 μM (cAK)[1]
References	[1]. Z X Lu, et al. Selective inhibition of cyclic AMP-dependent protein kinase by isoquinoline derivative. Biol Chem Hoppe Seyler. 1996 Jun;377(6):373-8