1984-15-2
1984-15-2 structure
- Name: Medronic Acid
- Chemical Name: medronic acid
- CAS Number: 1984-15-2
- Molecular Formula: CH6O6P2
- Molecular Weight: 176.002
- Catalog: Inorganic chemical industry Inorganic salt Phosphides, metal phosphoric acid, metaphosphoric acid, hypophosphorous acid and pyrophosphate
- Create Date: 2018-08-04 09:29:46
- Modify Date: 2026-07-03 10:18:45
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Medronic Acid (Methylenediphosphonic acid) is a methylene-substituted bisphosphonate. Medronic acid has affinity for and adheres to the surface of hydroxyapatite crystals in the bone matrix. This agent accumulates at sites of osteoid mineralization and can be used, complexed with radioisotopes in bone imaging.
| Name | medronic acid |
|---|---|
| Synonyms |
Medronic acid, Methanediylbis(phosphonic acid)
2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHOCHOL phosphonomethylphosphonic acid MDP,Medronic acid,Methylenediphosphonic acid methanediylbis(phosphonic acid) PHOSPHONOMETHYLPHOSPHONIC ACID Medronic acid, 10 mM in DMSO Clodronate Disodium Impurity 1 (Medronic Acid) Methylenediphosphonic acid Methylenebiphosphonic Acid acide méthanediylbis(phosphonique) [α,β-Methylene]diphosphoric acid Methanebisphosphonic Acid Phosphonic acid, P,P'-methylenebis Phosphonic acid, methylenebis Phosphonic acid, methylenedi Medronic acid [USAN:BAN:INN] Medronic METHYLENEDIPHOSPHONIC ACID FREE ACID medronicaci methylenediphosphonate EINECS 217-851-0 bis(dihydroxyphosphoryl)methane MDP METHYLENEDIPHOSPHONIC ACID ISO 9001：2015 REACH Methylenebisphosphonic acid Methandiylbis(phosphonsäure) MDP,Medronic acid MDP~Medronicacid Methylenediphosphonic acid, methylene diphosphoric acid, Methylenediphosphonic Acid methylene biphosphonate MethylenediphosphonicAcid> Methanediphosphonic Acid disodium hydrogen (hydrogen phosphonatomethyl)phosphonate METHYLENEDIPHOSPHONIC ACID METHYLENEBISPHOSPHONIC ACID Methylene diphosphophonic acid Phosphonic acid, P , P '-methylenebis MEDRONIC ACID Methylenebis(phosphonic acid) Methylene-1,1-bisphosphonic acid MFCD00002139 Medronic acid CRS Methylenediphosphonic acid, Medronic acid |
| Description | Medronic Acid (Methylenediphosphonic acid) is a methylene-substituted bisphosphonate. Medronic acid has affinity for and adheres to the surface of hydroxyapatite crystals in the bone matrix. This agent accumulates at sites of osteoid mineralization and can be used, complexed with radioisotopes in bone imaging. |
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| Related Catalog | |
| References |
| Density | 2.1±0.1 g/cm3 |
|---|---|
| Boiling Point | 583.2±60.0 °C at 760 mmHg |
| Melting Point | 197-199 °C(lit.) |
| Molecular Formula | CH6O6P2 |
| Molecular Weight | 176.002 |
| Flash Point | 306.5±32.9 °C |
| Exact Mass | 175.963959 |
| PSA | 134.68000 |
| LogP | -4.11 |
| Vapour Pressure | 0.0±3.5 mmHg at 25°C |
| Index of Refraction | 1.550 |
| Storage condition | 2-8°C |
| Symbol |
GHS05 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H314 |
| Precautionary Statements | P280-P305 + P351 + P338-P310 |
| Personal Protective Equipment | Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges |
| Hazard Codes | C: Corrosive; |
| Risk Phrases | R34 |
| Safety Phrases | S26-S36/37/39-S45 |
| RIDADR | UN 3261 8/PG 3 |
| WGK Germany | - |
| RTECS | SZ9138000 |
| Packaging Group | III |
| Hazard Class | 8 |
| HS Code | 2931900090 |
|
~97%
1984-15-2 |
| Literature: Rubino, Maria Teresa; Agamennone, Mariangela; Campestre, Cristina; Campiglia, Pietro; Cremasco, Viviana; Faccio, Roberta; Laghezza, Antonio; Loiodice, Fulvio; Maggi, Dariana; Panza, Emilia; Rossello, Armando; Tortorella, Paolo ChemMedChem, 2011 , vol. 6, # 7 p. 1258 - 1268 |
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1984-15-2 |
| Literature: Bulman Page, Philip C.; McKenzie, Michael J.; Gallagher, James A. Synthetic Communications, 2002 , vol. 32, # 2 p. 211 - 218 |
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~99%
1984-15-2 |
| Literature: Mohamady, Samy; Jakeman, David L. Journal of Organic Chemistry, 2005 , vol. 70, # 25 p. 10588 - 10591 |
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1984-15-2 |
| Literature: Journal of the American Chemical Society, , vol. 83, p. 1722 - 1726 |
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1984-15-2 |
| Literature: Zeitschrift fuer Naturforschung, Teil B: Anorganische Chemie, Organische Chemie, , vol. 31, p. 153 - 157 |
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1984-15-2 |
| Literature: Phosphorus, Sulfur and Silicon and Related Elements, , vol. 161, p. 75 - 96 |
| HS Code | 2931900090 |
|---|---|
| Summary | 2931900090. other organo-inorganic compounds. VAT:17.0%. Tax rebate rate:13.0%. Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward). MFN tariff:6.5%. General tariff:30.0% |