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52671-12-2

52671-12-2 structure

52671-12-2 structure

Name: [D-Lys6]-LH-RH
Chemical Name: pyr-his-trp-ser-tyr-d-lys-leu-arg-pro-gly-nh2
CAS Number: 52671-12-2
Molecular Formula: C₁₉H₁₇O₄P
Molecular Weight: 340.31000
Catalog: Signaling Pathways GPCR/G Protein GNRH Receptor
Create Date: 2017-07-29 12:03:58
Modify Date: 2026-07-12 17:27:43
[D-Lys6]-LH-RH is a Luteinizing-hormone-releasing hormone (LHRH) analogue. [D-Lys6]-LH-RH acts as a GnRH receptor agonist[1].

Name	pyr-his-trp-ser-tyr-d-lys-leu-arg-pro-gly-nh2
Synonyms	(D-LYS6)-GONADOTROPIN-RELEASING HORMONE [D-LYS6]-LH-RH (HUMAN) PGLU-HIS-TRP-SER-TYR-D-LYS-LEU-G-PRO-GLY-NH2 (2S)-N-[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2R)-6-amino-1-[[(2S)-1-[[(2S)-1-[(2S)-2-[(2-amino-2-oxoethyl)cbamoyl]pyrrolidin-1-yl]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-1-oxohexan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]-5-oxopyrrolidine-2-cboxamide (D-LYS6)-LUTEINIZING HORMONE-RELEASING HORMONE GLP-HIS-TRP-SER-TYR-D-LYS-LEU-G-PRO-GLY-NH2 lys(6)-lhr (D-LYS6)-LUTEINIZING HORMONE-RELEASING FACTOR PYROGLU-HIS-TRP-SER-TYR-D-LYS-LEU-G-PRO-GLY NH2 LHRH, Lys [D-LYS6]-LUTEINIZING HORMONE-RELEASING HORMONE (HUMAN) Luteinizing hormone-releasing factor (swine), 6-D-lysine

Description	[D-Lys6]-LH-RH is a Luteinizing-hormone-releasing hormone (LHRH) analogue. [D-Lys6]-LH-RH acts as a GnRH receptor agonist[1].
Related Catalog	Signaling Pathways >> GPCR/G Protein >> GNRH Receptor Research Areas >> Cancer Research Areas >> Endocrinology
In Vivo	[D-Lys6]-LH-RH (100 μg, minipumps implanted subcutaneously) inhibits tumor growth in Dunning R-3327H prostate cancer rats[1]. Animal Model: Dunning R-3327H prostate cancer rats[1] Dosage: 100 μg Administration: Alzet minipumps implanted subcutaneously Result: Inhibited tumor growth compared with control.

Density	1.51g/cm3
Molecular Formula	C₁₉H₁₇O₄P
Molecular Weight	340.31000
Exact Mass	340.08600
PSA	65.57000
LogP	5.02860
Index of Refraction	1.703

Risk Phrases	60
Safety Phrases	53-22-36/37/39-45

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